Registration Dossier
Registration Dossier
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EC number: 435-740-7 | CAS number: 94317-64-3
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- No information
- Author:
- Anonymous
- Year:
- 2 011
- Bibliographic source:
- NICNAS (Australia)
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- -
- EC Number:
- 435-740-7
- EC Name:
- -
- Cas Number:
- 94317-64-3
- Molecular formula:
- C4H14N3PS
- IUPAC Name:
- Phosphorothioic triamide, N-butyl-
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Vehicle:
- unchanged (no vehicle)
- Controls:
- no
- Amount / concentration applied:
- 80 mg
- Duration of treatment / exposure:
- 21 days
- Observation period (in vivo):
- 21 days
- Number of animals or in vitro replicates:
- 1
Results and discussion
In vivo
Results
- Irritation parameter:
- other: clinical observations
- Basis:
- animal #1
- Time point:
- other: 21 days
- Score:
- > 75
- Max. score:
- 110
- Reversibility:
- not fully reversible within: 21 days
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (irreversible effects on the eye)
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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