Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-736-8 | CAS number: 149-30-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of MBT to aquatic invertebrates (Dapnia magna) was tested according to OECD TG 202 "Daphnia sp. Acute Immobilisation test". After 48 hours of exposure an EC50 of 0.71 mg/L was obtained (National Institute of Technology and Evaluation, 1999).
MBT can be rapidly degraded by direct photolysis in water and the main degradation products appearing during the time frame of acute tests are benzothiazole (BT) and benzothiazolone (BTon) (Brownlee, 1992). The acute toxicity of BT to Daphnia magna was tested according to a guideline of U. S. Environmental Protection Agency (1975). The LC50 of 20 mg/l (nominal) and NOEC of 5.6 mg/l (nominal) were obtained (Analytical Bio-Chemistry Laboratories, Inc.,1978). According to OECD TG 202, the acute toxicity of BTon to Daphnia magna was determined to be a 48h-EC50 of 16.1mg/l (nominal). The nominal concentration was confirmed analytically (AKZO NOBEL, 2004).
There are some other benzothiazole derivatives as metabolites from MBT are considered as relevant for environmental exposure and risk assessment, such as MBTS and MeSBT. For MBTS no acute toxic effect was observed to Daphnia magna up to its water solubility (Bayer AG, 1993). The acute toxicities of MeSBT to Daphnia magna was tested according to OECD TG 202 and the 48h- EC50 of 29.8 mg/l (nominal) was determined, which was analytically confirmed (AKZO NOBEL, 2004).
Regarding the data summarized here, the described metabolites of MBT are less toxic to aquatic invertebrates than MBT itself.
Key value for chemical safety assessment
Additional information
MBT can be rapidly degraded by direct photolysis with a half-life time of ca. 30 mins (CMA, 1989) and can be rapidly oxidized in water by atmospheric oxygen with 60% conversion in 2 hours (Hansson & Agrup, 1993). MITI online did not provide detailed information, whether the effect concentrations were nominal concentrations or from analytical monitoring. The observed effect is most probably a combined effect from both MBT and its hydrolysis products like BT and oxidation product like MBTS, however BT and MBTS have much lower acute toxicities to aquatic invertebrates than MBT.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.