Registration Dossier
Registration Dossier
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EC number: 200-658-0 | CAS number: 67-52-7
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- OECD 105
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Type of method:
- flask method
Test material
- Reference substance name:
- Barbituric acid
- EC Number:
- 200-658-0
- EC Name:
- Barbituric acid
- Cas Number:
- 67-52-7
- Molecular formula:
- C4H4N2O3
- IUPAC Name:
- pyrimidine-2,4,6(1H,3H,5H)-trione
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- 10.4 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 2.5
- Remarks on result:
- other: mean of 3 measurements
Any other information on results incl. tables
Table 1: results of preliminary test
water for 0.1 g test item [mL] |
0.1 |
0.5 |
1 |
2 |
10 |
100 |
150 |
approximate solubility [g/L] |
> 1000 |
200 -1000 |
100 - 200 |
50 - 100 |
10 - 50 |
1 – 10 |
< 1 |
visual evaluation |
not soluble |
not soluble |
not soluble |
not soluble |
not soluble |
soluble |
soluble |
Table 2: results of flask method
Flask no |
Equilibration time at 20 °C [h] |
Test substance content [g/L] |
1 |
24 |
10.4 |
2 |
48 |
10.3 |
3 |
72 |
10.3 |
mean |
|
10.4 |
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
