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EC number: 481-150-8 | CAS number: 500011-86-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Additional physico-chemical information
Administrative data
- Endpoint:
- other: UV/Visible absorption spectrum and molar absorptivity
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 11/15/2005 - 06/23/2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Well documented GLP and OECD guidline study, conducted according to OECD 101.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 101 (1981)
- Deviations:
- no
- Remarks:
- The study was conducted according to the guideline in effect at time of study conduct.
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- -
- EC Number:
- 481-150-8
- EC Name:
- -
- Cas Number:
- 500011-86-9
- Molecular formula:
- C9H5BrClN3O2
- IUPAC Name:
- 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid
- Reference substance name:
- 1H-Pyrazole-5-Carboxylic Acid, 3-Bromo-1-(3-Chloro-2-Pyridinyl)-
- IUPAC Name:
- 1H-Pyrazole-5-Carboxylic Acid, 3-Bromo-1-(3-Chloro-2-Pyridinyl)-
- Reference substance name:
- DBC80
- IUPAC Name:
- DBC80
- Details on test material:
- Substance Identity: IN-DBC80
Empirical formula : C9H5BrClN3O2
Molecular weight : 302.52
Sample code : IN-DBC80
Appearance : Tan colour powder
Purity: 96.7%
Date of sample expiration: 07/22/2008
Lot No: 008
Constituent 1
Constituent 2
Constituent 3
Results and discussion
- Results:
- Preliminary test: The samples when initially scanned in triplicate from 200-750 nm showed no absorbance after 350 nm. Therefore the definitive testing was conducted for all the samples from 200 to 350 nm.
Definitive test: The molar absorption coefficients were calculated for the absorption maxima at each pH. The molar absorption coefficients for the pH 1.8 buffer were determined to be 40331, 39998, 37980 L mol-1 cm-1, for the 7.2, 6.0 and 5.0 μg/ml solutions respectively. The molar absorption coefficients for the pH 7.0 buffer were determined to be 59269, 63549, 63434 L mol-1 cm-1, for the 7.2, 6.0 and 5.0 μg/ml solutions respectively. The molar absorption coefficients for the pH 10.0 buffer were determined to be 42875, 42598, 41616 L mol-1 cm-1, for the 7.2, 6.0 and 5.0 μg/ml solutions respectively.
Any other information on results incl. tables
All verification tests indicated that the instrument was performing correctly and accurately. The temperature was maintained at 25 ± 0.5°Celcius during the analysis. The UV/visible spectra of the 7.2, 6 and 5 ug/mL test substance solutions at pH 1.8, 7 and 10 showed absorption maxima (lamda max) at 215 nm. The blank versus blank scans showed no absorbance readings varying more than ± 0.05 from the nominal zero value.
Applicant's summary and conclusion
- Conclusions:
- The UV/visible spectra of IN-DBC80 under acidic, neutral and basic conditions showed absorption maxima at 215 nm for the 7.2, 6 and 5 μg/mL test solutions. The molar absorption coefficients for the pH 1.8 buffer were determined to be 40331, 39998, 37980 L mol-1 cm-1, for the 7.2, 6.0 and 5.0 μg/ml solutions respectively. The molar absorption coefficients for the pH 7.0 buffer were determined to be 59269, 63549, 63434 L mol-1 cm-1, for the 7.2, 6.0 and 5.0 μg/ml solutions respectively. The molar absorption coefficients for the pH 10.0 buffer were determined to be 42875, 42598, 41616 L mol-1 cm-1, for the 7.2, 6.0 and 5.0 μg/ml solutions respectively.
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