Registration Dossier
Registration Dossier
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EC number: 253-168-4 | CAS number: 36727-29-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound 3,5,5-trimethylhexanoyl chloride: Acutely harmful to aquatic algae. With high probability acutely not harmful to aquatic algae after neutralisation of the test item.
Hydrolysis product 3,5,5-trimethylhexanoic acid: Acutely harmful to aquatic algae.
Key value for chemical safety assessment
Additional information
The parent compound was tested according to DIN 38412, Part 9 with the green algae Desmodesmus subspicatus as test organis. The resulting ErC50 (72 h) was 40.8 mg/L. When the parent compound was neutralised, the ErC50 (72 h) increased to 311.7 mg/L. The resulting ErC10 (72 h) was 26.3 mg/L, and 108.1 mg/L when neutralised (BASF AG, 1990).
The growth inhibiting effect of the hydrolysis product 3,5,5-trimethylhexanoic acid was investigated in a 72-h study according to OECD 201 with the green alga Pseudokirchneriella subcapitata. The test substance concentrations were analytically verified. The recovery rates were between 91 and 103%, therefore the results are based on nominal concentrations. The validity criteria of OECD TG 201 were fulfilled. Based on nominal concentrations, the ErC50 was 81 mg/L. The 72-h ErC10 was 45 mg/L and the NOEC was 10 mg/L for growth rate and yield (Harlan, 2010/C84132). Based on the EC50 3,5,5-trimethylhexanoic acid is considered acutely harmful to algae.
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