Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 429-220-9 | CAS number: 132584-17-9
Specific investigations: other studies
Administrative data
- Endpoint:
- specific investigations: other studies
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
- Principles of method if other than guideline:
- Test procedure:
OECD guideline 486, adopted 21st July 1997
Results and discussion
- Details on results:
- Clinical signs (including activity and piloerection) were
observed at both dose levels of the test substance after the
second administratioin. One animal dosed at 2000 mg/kg was
found dead shortly before the start of liver perfusion.
The viability of the hepatocytes was not substantially
affected by the in vivo treatment with the test item at any
of the dose groups.
None of the tested dose levels revealed UDS induction in the
hepatocytes of the treated animals as compared to the
corresponding vehicle control.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
