Registration Dossier
Registration Dossier
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EC number: 273-794-1 | CAS number: 69029-48-7 Product from the pH-adjustment of indium-rich solutions causing the precipitation of indium, ammonium and cadmium hydroxides and sulfates and zinc sulfate.
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation, other
- Remarks:
- CLP calculation method
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- other: software
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
- Principles of method if other than guideline:
- Acute toxicity of UVCB substance was determined by classifying based on Mixture rules from EU CLP (tier 2=summation of classified components to derive Hazard class)
- GLP compliance:
- no
- Remarks:
- equivalent quality assurance
Test material
- Reference substance name:
- Indium, cake
- EC Number:
- 273-794-1
- EC Name:
- Indium, cake
- Cas Number:
- 69029-48-7
- IUPAC Name:
- Insoluble indium-containing residue after precipitation of indium bearing solutions
Constituent 1
In vivo test system
Test animals
- Species:
- other: standard species relevant to skin sensitisation classification
Results and discussion
In vitro / in chemico
Results
- Remarks on result:
- not measured/tested
- Remarks:
- prediction
Any other information on results incl. tables
For the worst case sample only, the calculated classification via additivity method resulted in an "skin sensitisation cat 1" classification for the UVCB substance (toxicity of all metal constituents are known from 1st ATP CLP + all assessed metals). The result is mainly driven by Co.
Applicant's summary and conclusion
- Conclusions:
- Good quality study that can be used to derive classification of the UVCB substance and predict hazard. Note toxicities of constituents/species as of 1st ATP CLP + assessed metals
- Executive summary:
The study provided a conservative (lower tier) estimate of the skin sensitisation: classification of boundary sample is skin sensitisation cat. 1
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