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EC number: 251-846-4 | CAS number: 34140-91-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 6.46 µg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 4.1 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.646 µg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 388 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 38.8 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 11.1 mg/kg soil dw
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential to cause toxic effects if accumulated (in higher organisms) via the food chain
Additional information
PNECs are based on the following data for the test substance:
Test type | Results |
Microorganisms, activated sludge | 3h-NOEC respiration: 993.2 mg/L |
Short-term studies |
|
Daphnia magna | 21d-EC50: 1.40 mg/L |
Danio rerio | 96h-LC50: 1.34 mg/L |
Pseudokirchneriella subcapitata | 72h-ErC50: 0.41 mg/L |
Chronic studies |
|
Pseudokirchneriella subcapitata | 72h-ErC10: 0.323 mg/L |
Daphnia magna | No long-term effects were observed during the chronic daphnia test. |
Terrestrial studies |
|
Eisenia fetida | 56d-NOEC reproduction, biomass, mortality: 993.2 mg/kg soil dw |
As long-term NOECs from species representing two trophic levels are available (algae and daphnia) an assessment factor of 50 may be used du derive the PNEC freshwater. With the same motivation, an AF of 500 has been used for the derivation of PNEC marine.
According to REACH Annex IX, long-term toxicity testing for daphnia and fish (according to TG OECD 211 and 210) has been proposed with two Testing Proposal in order to perfrom these studies with standard OECD medium. An Algae study (OECD 201) with a similar substance is available to assess the inhibition of the growth of the freshwater green alga Pseudokirchneriella subcapitata in a standard medium. Due to the complex structure of the test item, and the very low solubility the WSF approach was used for ecotoxicity testing. When the full dataset in standard medium will be available, the key value for chemical safety assessment will be re-assessed.
No tests were performed with sediment organisms. The PNECs for this sediment is derived using the equilibrium partitioning method.
For the terrestrial compartment, one long-term study (OECD 222) is available showing no effects as the 56-d NOEC of the substance was = 993.2 mg/kg dw. According to the guidance, when only one test result with soil dwelling organisms is available the risk assessment is performed both on the basis of this result using assessment factors and on the basis of the equilibrium partition method (EPM , see above; Kp,soil = 30068). From both PECsoil/PNECsoil ratios the highest one is chosen for the risk characterisation. Therefore, the PNEC was calculated both based on the long term study as well as the EPM. The PNEC soil based on EC10 from earthworm reproduction test (OECD 222, reliability 1) and an assessment factor of 100. This would result in a PNEC of 9.93 mg/kg dw. PNEC soil based on the EPM is derived from PNEC freshwater, using the equilibrium partitioning method and resulting in a PNEC soil of 38,5 mg/kg dw. As the PEC soil is independent of the calculation method, the PNEC soil derived from the long term study will result in the highest PECsoil/PNECsoil ratios and is therefore chosen for the risk characterization: the PNECsoil is 9.93 mg/kg dw.
Conclusion on classification
For classification purposes Ecotoxicity, Biodegradability and Bioconcentration have to be considered.
Ecotoxicity
Due to intrinsic properties of the test substance, river water ecotoxicity tests are available on the registered susbtance. As river water has a mitigating effect on ecotoxicity due to sorption to DOC and suspended matter, a factor of 10 should be applied to the L(E)Cx and NOEC to correct for the lower ecotoxicity observed. Algae are in general the most sensitive species and are therefore the basis for classification of N-[(9Z)-octadec-9-en-1-yl]propane-1,3-diaminium di[(9Z)-octadec-9-enoate]. It should be noted that the 21day-daphnia EC50 is included in the table below for classification purposes as a worst-case for acute toxicity in river water tests.
The classification is based on the following aquatic toxicity data for the test substance:
Test type | Results | Correction for river water with factor 10 |
|
|
|
Short-term studies |
|
|
Danio rerio | 96h-LC50: 1.34 mg/L | 134 µg/L |
Daphnia magna | 21d-EC50 adult mortality: 1.40 mg/L | 140 µg/L |
Pseudokirchneriella subcapitata | 72h-ErC50: 410 ug/L | 41 µg/L |
Chronic studies |
|
|
Daphnia magna | 21 -NOEC = 1.35 mg/L | 0.135 mg/L |
Pseudokirchneriella subcapitata | 72h-ErC10: 323 µg/L | 32.3 µg/L |
Biodegradability
The substance is rapidly biodegradable in the environment as demonstrated according to an OECD TG 301 F test. The biodegradation percentage was >60% after 28 days.
Conclusion classification according to CLP Regulation 1272/2008
Based on the results of the acute aquatic toxicity (values < 1 mg/L) the substance is classified with Category Acute 1 (M-factor 10).
Reliable chronic toxicity data are available for crustacea and algae with chronic EC10 resp 1.35 mg/L and 0.323 mg/L. In addition the substance is readily biodegradable. Based on the lowest results of the chronic aquatic toxicity (0.01 < corrected ErC10 < 0.1 mg/L) and since the substance is rapidly biodegradable, the substance is classified with Category Chronic 2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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