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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: No details on study. Secondary source is reliable.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Xylidine, BUA Stoffbericht 161
Year:
1994
Bibliographic source:
BUA, Beratergremium für umweltrelevante Altstoffe (BUA) der Gesellschaft Deutscher Chemiker, S.Hirzel Verlag 1995
Reference Type:
publication
Title:
Acute toxicity and skin corrosion data for some organic and inorganic compounds and aqueous solutions
Author:
Vernoth et. al.
Year:
1977
Bibliographic source:
Toxicol. Appl. Pharmacol. 42, 417-423
Reference Type:
secondary source
Title:
Database value
Year:
2011
Bibliographic source:
ACToR Database

Materials and methods

Principles of method if other than guideline:
no data available
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
2,3-xylidine
EC Number:
201-755-0
EC Name:
2,3-xylidine
Cas Number:
87-59-2
Molecular formula:
C8H11N
IUPAC Name:
2,3-dimethylaniline

Test animals

Species:
rat
Strain:
not specified
Sex:
male

Administration / exposure

Control animals:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
930 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion