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EC number: 256-283-8 | CAS number: 46830-22-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Adequacy of study:
- other information
- Study period:
- 21/11/1994-25/11/1994
- Rationale for reliability incl. deficiencies:
- other: Well documented report of a guideline study conducted to GLP.
Data source
Reference
- Title:
- Unnamed
- Year:
- 1 995
- Report date:
- 1995
Materials and methods
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- - Name of test material (as cited in study report): ADAMQUAT BZ 80
- Physical state: Clear yellow liquid.
- Analytical purity: 80.4
- Impurities (identity and concentrations): water - 19.6%, EMHQ (stabiliser) - 337 ppm
- Composition of test material, percentage of components: 100%
- Purity test date: 28/07/1994
- Lot/batch No.: BZ 008
- Expiration date of the lot/batch: not specified
- Stability under test conditions: stable
- Storage condition of test material: at room temperature and away from light
Constituent 1
Sampling and analysis
- Details on sampling:
- A sample of 4 ml was taken on 3 occasions during the test (at the beginning [T0]; just before changing the first solution [T 24]; at the end of the test [T 96]). As the test substance was found not to be toxic at the limit test concentration of 100 mg/l (maximum) the study was considered as complete and samples were analysed.
Test solutions
- Details on test solutions:
- DILUTION WATER: Filtered and dechlorinated potable water, which was then softened by a Permo water softening system. Half of the water passed directly into a holding tank attached to the flow through system while the remaining half first passed through a deioniser producing ultra-pure water, which was then fed into the holding tank. The test substance was dissolved in aqueous solution at 100mg/l, agitated mechanically for 24 hours in an attempt to completely dissolve the test substance. This stock solution was then used to prepare the test solutions directly.
Test organisms
- Details on test organisms:
- TEST ORGANISM
- Common name: Rainbow Trout
- Source: "Labbas", Acquigny, 27400 Louviers, France
- Length at study initiation (length definition, mean, range and SD): The animals were an average of 47.7 mm long, ranging from 40 to 54 mm.
- Feeding during test: Animals were not fed during test.
ACCLIMATION
- Acclimation period: Animals were acclimated for 7 days in a flow-through system in water (same quality used in the test).
- Type and amount of food:not specified
- Feeding frequency: twice daily ceasing 24 hours before the start of the test
- Health during acclimation (any mortality observed): no adverse effects specified
Study design
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 140±20 mg/l as CaCO3.
- Test temperature:
- 13-17°C.
- pH:
- 7.31-7.77
- Dissolved oxygen:
- Oxygen concentration: maintained at > 60%of the air saturation value at 13-17°C.
- Nominal and measured concentrations:
- Nominal concentrations: 0.1, 1, 10, 100 mg/l.
- Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Type: not specified
- Material, size, headspace, fill volume: not specified
- Aeration: not used
- No. of organisms per vessel: 5 fish per concentration at the following nominal concentrations: 0.1, 1, 10mg/l. 7 fish for the nominal concentration 100mg/l.
- No. of vessels per concentration (replicates): 1
- Biomass loading rate: The mean weight based on sample of 10 fish removed at random from the acclimatisation tank was 1.62g, equivalent to a loading of 0.76 g/l in the limit test.
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: : Filtered and dechlorinated potable water, which is then softened by a Permo water softening system. Half of the water passes directly into a holding tank attached to the flow through system while the remaining half first passes through a deioniser producing ultra-pure water, which is then fed into the holding tank.
- Total organic carbon: not specified
- Particulate matter: not specified
- Metals: not specified
- Pesticides: not specified
- Chlorine: not specified
- Alkalinity: not specified
- Ca/mg ratio: not specified
- Conductivity: not specified
- Intervals of water quality measurement: 24 hours
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: A light/dark cycle of 16/8 hours.
- Light intensity: not specified
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : Mortality or visible abnormalities.
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Effect conc.:
- 100 mg/L
- Details on results:
- Mortality in the control and the limit test concentration of 100 mg/l was 0%.
No mortality or clinical signs were observed.
Applicant's summary and conclusion
- Conclusions:
- ADAMQUAT BZ was non-toxic to Onchorhynchus mykiss at 100 mg/l in a semi-static test system during a 96-hour exposure period. The LC0 was 100 mg/l (the highest test concentration).
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