Registration Dossier
Registration Dossier
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EC number: 229-563-2 | CAS number: 6610-29-3
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: 4e: Documentation insufficient for assessment.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 980
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Rats were exposed one hour to an atmospheric concentration of 0.4 mg compound per liter air.
- GLP compliance:
- not specified
- Limit test:
- no
Test material
- Reference substance name:
- 4-methylthiosemicarbazide
- EC Number:
- 229-563-2
- EC Name:
- 4-methylthiosemicarbazide
- Cas Number:
- 6610-29-3
- Molecular formula:
- C2H7N3S
- IUPAC Name:
- 1-amino-3-methylthiourea
- Details on test material:
- no data
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Vehicle:
- other:
- Duration of exposure:
- 1 h
- Concentrations:
- 0.4 mg/l
- No. of animals per sex per dose:
- no data
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC0
- Effect level:
- > 0.4 mg/L air
- Exp. duration:
- 1 h
- Mortality:
- No deaths were reported
- Clinical signs:
- other: No toxic effects were noted.
Applicant's summary and conclusion
- Conclusions:
- Signs of toxicity were not observed when rats were exposed one hour to an atmospheric concentration of 0.4 mg/ml of MTSC. The crystalline nature of MTSC probably reduces inhalational hazards.
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