Registration Dossier
Registration Dossier
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EC number: 903-945-5 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The reaction mass of CDFA and TFA is not harmful to daphnia with a 48hEC50 higher than 100 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
One reliable key study on acute toxicity to aquatic invertebrates is available on the reaction mass of chlorodifluoroacetic acid (CDFA) and trifluoroacetic acid (TFA).
The objective of this study (2008) was to determine, through a screening test, the acute toxicity of reaction mass of CDFA and TFA (named "CDFA CRUDE" in the study report) to Daphnia magna. On the day of the test, a stock solution of 1000 mg/L of the test item was prepared in the test medium. The pH of the stock solution was adjusted with sodium hydroxide solution 1N (initial pH: 2.20 ; final pH: 7.62). The concentrations of 100 mg/L; 32 mg/L; 10 mg/L; 3.2 mg/L and 1.0 mg/L were obtained by diluting the stock solution in the test medium in order to get the desired experimental concentrations. The test was carried out with pH adjustment of the stock solution. Four replicates with five animals were exposed to each concentration. No immobilization has been observed during the study. Therefore, the 48hEC50 is > 100 mg/L.
Based on these results, reaction mass of CDFA and TFA is not harmful to Daphnia.
This conclusion is supported by the available key study on TFA which shows no immobility at the tested concentration of 999 mg/L..
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