Registration Dossier
Registration Dossier
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EC number: 208-173-6 | CAS number: 513-85-9
Endpoint summary
Administrative data
Description of key information
Oral: The acute oral LD50 was determined to be > 5000 mg/kg bw in rats.
Inhalation: No mortality was observed in an inhalation risk test with a saturated vapor (LD50 > 0,85 mg/l) in rats.
Key value for chemical safety assessment
Additional information
Oral
The test article 2,3 -butandiol was administered to 10 rats (5 male and 5 female). Observation period was 14 days. The oral LD50 was determined to be > 5000 mg/kg bw. Clinical signs observed were dispnoe, apathy, staggering. [BASF 1980]
Inhalation
No mortality was observed when 12 rats were exposed for 7 h to an atmosphere that has been saturated at 20°C with the volatile part of the compound (LC50 > 0,85 mg/l). [BASF, 1980]
Oral
The test article 2,3 -butandiol was administered to 10 rats (five male and 5 female). Observation period was 14 days. The oral LD50 was determined to be 5000 mg/kg bw. Clinical signs observed were dispnoe, apathy, staggering.
Inhalat
Justification for classification or non-classification
No classification and labelling for acute oral and inhalation toxicity is necessary according to Directive 67/548/EEC(DSD) or Regulation (EC) No 1272/2008 (GHS (EU-CLP)) criteria.
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