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EC number: 236-882-0 | CAS number: 13531-52-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The log Pow was determined to be -1.67 at 23 °C and pH 10.8.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -1.67
- at the temperature of:
- 23 °C
Additional information
The partition coefficient octanol/water of the test item was determined in a GLP study (BASF SE, 14L00303) according to OECD 107. In a pre-test the miscibility of the test item in n-octanol was investigated. The test item was miscible in n-octanol and water in any ratio (please refer to IUCLID section 4.8). Thus, a nominal concentration of 1 g/L and a volume ratio n-octanol / water of 1:2, 1:1 and 2:1 were applied. Using the shake flask method the log Pow of the test item was determined to be -1.67 at 23 °C and pH 10.9. In the course of the study no buffered solution were used. Thus, the logPow refers to the partly dissociated form of the test item.
In addition the partition coefficient octanol / water was calculated using QSAR. Using KOWWIN v1.68 the log Kow of the substance was calculated to be -1.64 at 25 °C. The result refers to the uncharged form of the test item. The substance is within the applicability domain of the model. Thus, the calculated value was regarded as reliable.
In a supplementary non-GLP study (BASE SE, BRU 89.028) according to OECD 107 the log Pow of the test item was Investigated. Using the shake flask method the log Pow was determined to be -1.37 at 25 °C and pH 11.2 without pH adjustment.
In the two available studies the logPow was determined in unbuffered test solutions. Taking the pKa values into account (please refer to IUCLID section 4.21) it was concluded that at pH 11 the test item was present in a partly dissociated form. Thus, the degree of dissociation was estimated to be about 70 per cent. The logPow determined by EpiSuite refers to the uncharged form of the test item. The differences between the experimental determined logPow and the calculated value were minimal (-1.67 vs -1.64). Therefore it can be concluded that logPow study using a buffered test solution will only yield slightly different results.
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