Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-472-8 | CAS number: 107-20-0
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary literature
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity Profile of Chloroacetaldehyde
- Author:
- W.H. Lawrence, E.O. Dillingham, J.E. Turner, J. Autian
- Year:
- 1 972
- Bibliographic source:
- Journal of Pharmaceutical Sciences, Vol. 61, No. 1, Jan. 1972
- Report date:
- 1971
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Postobservation period 7 days
- GLP compliance:
- not specified
- Limit test:
- no
Test material
- Reference substance name:
- Chloroacetaldehyde
- EC Number:
- 203-472-8
- EC Name:
- Chloroacetaldehyde
- Cas Number:
- 107-20-0
- Molecular formula:
- C2H3ClO
- IUPAC Name:
- 2-chloroacetaldehyde
- Test material form:
- other: solution in water
- Details on test material:
- 30 % solution in water, purity not reported.
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- water
- No. of animals per sex per dose:
- 4 animals
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- ca. 60 mg/kg bw
- Based on:
- test mat.
- 95% CL:
- ca. 39 - ca. 91
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
