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EC number: 806-508-6 | CAS number: 1419212-77-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.20 (Daphnia magna Reproduction Test)
- Principles of method if other than guideline:
- In view of the low solubility of the substance a water accomodated fraction was tested
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and citric acid
- EC Number:
- 700-795-0
- Cas Number:
- 1393571-43-1
- Molecular formula:
- NA
- IUPAC Name:
- Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and citric acid
- Test material form:
- other: extremely viscous liquid
- Details on test material:
- test substance identification: Fatty acids, tall-oil, reaction products with fatty acids C16-18 and C18-unsatd, branched and linear, diethylenetriamine and citric acid
Description : dark amber coloured extremely viscous liquid
Constituent 1
- Specific details on test material used for the study:
- Physical state/Appearance: Dark amber colored solid block
Batch: Development sample 15-11-1
Storage Conditions: Room temperature in the dark
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 0 and 100 mg/L
- Sampling: duplicate samples from fresh solutions on day 0, 5, 9, 14 and 19 and from old solutions on day 2, 7, 12, 16 and 21 of all replicates (analyses on pooled replicate samples)
- Sample storage conditions before analysis: frozen
Test solutions
- Vehicle:
- no
- Details on test solutions:
- - Pre-treatment: prior to weighing the substance was heated for30 min to 3 hours at 70°C
- Method: stirring for 23 hours, standing 1 hour and transfer via tube by mid depth syphoning
- Differential loading: 100 mg/L (500 mg in 5L water)
- Controls: untreated
- Evidence of undissolved material: microscopic evaluation did not show any microdispersions or undissolved material in the WAF
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Source: in-house laboratory culture
- Age of parental stock : <24 hours
- Feeding during test: daily to achieve 0.1-0.2 mg C/daphnid/day
- Food type: algae suspension ( 5 to 10 µL) and Tetramin® flake food suspension (20 µL)
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 21 d
- Remarks on exposure duration:
- according to the guideline
Test conditions
- Hardness:
- 250-270 as mg/L CaCO3
- Test temperature:
- 21-22 °C
- pH:
- 7.7-8.1
- Dissolved oxygen:
- 8.3-9.0 mg/L (>93% of saturation)
- Nominal and measured concentrations:
- nominal 0 and 100 mg/L
measured:- Details on test conditions:
- TEST SYSTEM
- Test vessel: 150 mL glass vessel containing 100 mL test medium
- Type: closed
- Aeration: none
- Renewal rate of test solution: on day 0. 2, 5, 7, 9, 12, 14, 16 and 19.
- No. of organisms per vessel: 1
- No. of vessels per concentration (replicates): 10
- No. of vessels per control (replicates): 1
- No. of vessels per vehicle control (replicates): 10
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: reconstituted water (Elendt M7 medium)
- pH medium: 7.9 ± 0.3
OTHER TEST CONDITIONS
- Adjustment of pH: none
- Photoperiod: 16 light/ 8 dark
- Light intensity: 571 to 691 lux
EFFECT PARAMETERS MEASURED :
daily mortality parental daphnids; number of F1 daphnia and (discarded) unhatched eggs
at renwals: number of young daphnids (live and dead) and unhatched eggs as saved on the mesh
TEST CONCENTRATIONS
- Range finding study: the results were not evaluated, test substance concentration can be based on the outcome of the acute daphnia test
- Test concentrations: 0 and 100 mg/L
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 21 d
- Dose descriptor:
- NOELR
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (total fraction)
- Remarks:
- loading rate
- Basis for effect:
- reproduction
- Remarks:
- and immobilisation
- Key result
- Duration:
- 21 d
- Dose descriptor:
- EL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (total fraction)
- Remarks:
- loading rate
- Basis for effect:
- immobilisation
- Key result
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (total fraction)
- Remarks:
- loading rate
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- EL10
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (total fraction)
- Remarks:
- loading rate
- Basis for effect:
- morphology
- Remarks:
- length
- Details on results:
- - Behavioural abnormalities:
- Observations on body length and weight: no treatment related effects (day 21 control 3.8 mm, 1000 mg/L 4.1 mm)
- Mortality of control: 0
- First young: day 9 in controld and 100 mg/L
- Reported statistics and error estimates:
- t-test showed no statistically significant differences (P≥ 0.05) between the control and the 100 mg/L regarding length and number of young produced.
Any other information on results incl. tables
Nominal Loading Rate (mg/L) |
Total Number of Live Young |
Percentage Survival of Parental (P) Generation |
Number of Live Young Per Parent Surviving to the End of the Test |
control |
1237 |
100 |
124 |
100 |
1278 |
100 |
128 |
No parental accidental and inadvertent mortalities reported
There were no unhatched eggs or dead young in any of the control or treatment groups. There were no visible differences in condition between young in the treatment and control groups.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The substance did not affect immobility and reproduction of daphnia exposed at 100 mg/L. The NOELR/EL10 is 100 mg/L
- Executive summary:
Daphnids were exposed to 0 and 100 mg/L test substance during 21 days. Renewal of the test solutions was done 3 times weekly. No immobility was found or other adverse effects on the parental daphnids. Reproduction was comparable between the treated and control daphnids. The analyses for accuracy of preparation at the maximum concentration attainable showed that the actual concentration was below the LOQ (0.021 mg/L).
The NOELR is 100 mg/L.
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