Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 202-777-3 | CAS number: 99-66-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Review paper
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 2007
Materials and methods
Test guideline
- Guideline:
- other: No data
- Deviations:
- not specified
- Principles of method if other than guideline:
- No data
- GLP compliance:
- not specified
- Test type:
- other: No data
Test material
- Reference substance name:
- 2-propylvaleric acid
- EC Number:
- 202-777-3
- EC Name:
- 2-propylvaleric acid
- Cas Number:
- 99-66-1
- Molecular formula:
- C8H16O2
- IUPAC Name:
- 2-propylpentanoic acid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Doses:
- No data
- No. of animals per sex per dose:
- No data
- Control animals:
- not specified
- Statistics:
- No data
Results and discussion
- Preliminary study:
- No data
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- ca. 670 mg/kg bw
- Mortality:
- No data
- Clinical signs:
- other: No data
- Gross pathology:
- No data
Applicant's summary and conclusion
- Interpretation of results:
- Toxicity Category IV
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Valproic acid has a reported LD50 (oral rat) of 670mg/kg
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
