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EC number: 251-529-0 | CAS number: 33456-68-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Auto flammability
Administrative data
- Endpoint:
- auto-flammability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted by a well experienced research laboratory and in accordance with several internationally acknowledged guidelines.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
- Principles of method if other than guideline:
- Equipment:
An oven with a quartz intern wall ((Ø = 36,5 mm; H = 220 mm), which can go up to the rnaximum ternperature of 600°C, and a dispersion device
constitute the equipment.
The oven is controlled by a thermocouple placed in the quartz tube wall with a temperature regulator.
The powder dispersion device is constituted by a container in which he sample is placed, a pressure reducer, a small device with a manometer and
the fluid to disperse (air or oxygen-nitrogen mixture) and one electrovalve.
The reducer regulates the optimum deposit pressurisation value and when the experiment takes place the electrovalve opening is controlled to
obtained, with the gassy fluid flow, the powder transport and consequent powder dispersion in the oven (the powder placed in the container)
Procedure:
Approximately 100mg of the powder to examine are placed in the container, if possible with a particle size less than 75mm; when the oven
temperature is near the desired value, the powder dispersion in the oven, putting on the electrovalve, is done.
The electrovalve opening allow the small deposit of gassy fluid, previously stored at the pressure value (0, 1 - 2 bar) appropriate for the powder
typology, to flow.
The dispersion production can be observed by a mirror placed inside the reactor, if there is no phenomenon visible the test will be repeated at
superior temperature, from 10°C to 10°C. Otherwise if the powder cloud ignition is manifested, the test will be repeated at inferior temperature, from 10°C to 10°C, until reach the minimum ignition temperature.
More tests are done, varying the powder quantity used, as weil as the deposit fluid pressure, with the target of determine the minimum temperature at which the ignition of the cloud takes place.
lt is assumed as ignition temperature in cloud of the sample to exam, the minimum oven temperature value which result is positive and minor than
10°C. - GLP compliance:
- not specified
Test material
- Reference substance name:
- p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide
- EC Number:
- 251-529-0
- EC Name:
- p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide
- Cas Number:
- 33456-68-7
- Molecular formula:
- C20H22N2O5S
- IUPAC Name:
- 4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene-1-sulfonamide
Constituent 1
Results and discussion
Auto-ignition temperature (liquids / gases)
- Auto-ignition temperature:
- 460 °C
- Remarks on result:
- other: Dust cloud ignition temperatur
Relative self-ignition temperature (solids)
- Relative self-ignition temperature:
- 460 °C
- Remarks on result:
- other: Dust cloud ignition temperatur
Any other information on results incl. tables
The ignition temperature in cloud of the examined sample, that has been obtained dispersing the powder directly in the assay equipment, is represented in the following table.
Sample | Tcloud (°C) |
Fase X (ARDF-26) | 460 |
Applicant's summary and conclusion
- Conclusions:
- The dust cloud ignition temperature is moderately high, because this, furthermore to avoid the dust cloud formation, you must avoid to hand it near to surfaces at this temperature
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