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Diss Factsheets
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EC number: 249-894-6 | CAS number: 29857-13-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
The Guidance on information requirements and chemical safety assessment, Chapter R.7C: Endpoint specific guidance (June 2017), section R. 7.11.6.3, Table R.7.11-2, page 158, specifies the information needed to waive the terrestrial studies based on soil hazard categories.
The registered substance has a log Pow <3 and is inherently biodegradable. Therefore, accumulation and persistence of the registered substance in soil and organisms is very unlikely. Furthermore, although the registered substance might adsorb to soil (estimated log Koc = 3.8), it is not expected to cause adverse effects on terrestrial organisms based on a PNEC soil derived from a chronic earthworm study. Consequently, further terrestrial toxicity tests are not needed.
Further argumentation for the waiving of the terrestrial plant study:
- In acute aquatic tests, fish and daphnids were by a factor of > 35 more sensitive than aquatic algae (fish LC50: 0.88 mg/L, acute Daphnia EC50: 2.4 mg/L, algae ErC50 93 mg/L). This is also valid when comparing chronic data (EC10 daphnids: 0.15 mg/L, ErC10 algae: 7.8 mg/L.). Therefore, aquatic algae are not the relevant species for the aquatic risk assessment.
- Based on the results from the aquatic environment, i.e., invertebrates are more sensitive than algae, it can also be assumed that the terrestrial plants are less sensitive compared to terrestrial invertebrates. A chronic earthworm study resulted in a NOEC of 104 mg/kg dw. Considering the aquatic tests, this NOEC is considered to be conservative. This NOEC value resulted in PEC/PNEC << 1 for the soil compartment in every usage covered by the chemical safety assessment. Hence, there is no indication that a plant test will provide further information for the risk assessment of this substance.
- If, however, a terrestrial plant test would be performed, data from two trophic levels would be available and hence an assessment factor of 50 instead of 100 could be used for the risk assessment according to the current guidance documents. Assuming that the plants are not more sensitive than the earthworms, this would result in a higher PNEC. Hence, not performing the terrestrial plant test is considered to be conservative.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.