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EC number: 230-601-5 | CAS number: 7214-18-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A 72-h ErC50 and ErC10 values are 3.8 and 1.17 mg/L, respectively, based on ECOSAR prediction using the measured log Kow of 3.8.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 3.08 mg/L
- EC10 or NOEC for freshwater algae:
- 1.17 mg/L
Additional information
The acute algae ErC50 for the neutral organic substance Verdol is predicted to be 3.08 mg/l based on the ECOSAR SAR for neutral organics using a measured log Kow of 3.8, molecular weight of 156.27 and the equation: Log 96h-ErC50 (mmol/L) = -0.6922 log Kow + 0.9253. When using the predicted log Kow value of 3.42, the 96h EC 50 is 5.67 mg/l. The 96-h EC50 is considered equivalent to the 72h current exposure time in the OECD TG 201 test.
The chronic algae EC10 for the neutral organic substance Verdol is predicted to be 1.17 mg/l based on the ECOSAR SAR for neutral organics using a measured log Kow of 3.8, molecular weight of 156.27 and the equation: Log 96h-Chv (mmol/L) = -0.5583 log Kow -0.4017. When using the predicted log Kow value of 3.42, the 96h EC 10 is 1.99 mg/l. The ChV is considered equivalent to the EC10 in the OECDTG 201 test
Verdol is in the applicability domain of the ECOSAR prediction because: a) the substance is a neutral organic presenting the toxicity solely by its bioavailability (i.e. without fragments that activate this chemical class); b) its log Kow is 3.8 (=< 6.4); c) its MW is 156.27 (< 1000); and; d) the toxicity predicted is below its water solubility of 613 mg/l.
The measured and predicted log Kow values of the substance are 3.8 and 3.41, respectively and therefore present limited uncertainty as the log Kow difference is < 0.5. Also, the measured log Kow of 3.8 is used presenting a conservative value (a lower EC50).
This shows that the prediction is reliable and a Klimisch 2 can be assigned. In accordance with REACH Annex XI, the validity of the (Q)SAR is documented in a QMR for acute and chronic algae toxicity on neutral organics. The adequate and reliable documentation presented, further supports this prediction.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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