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Diss Factsheets
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EC number: 952-791-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
In accordance with column 2 Annex IX section 9.1 of Regulation (EC) No 1907/2006 (REACH), the study on long-term toxicity to fish does not need to be conducted because from the available acute data for structural analogue substances and the chronic data that are available for all 3 trophic levels, there is no indication that fish are any more sensitive than aquatic invertebrates and algae to this substance. Furthermore, performing the chronic fish study, a vertebrate study falling under the animal protection legislation of the EU (86/609/EEC), is unjustified.
However, for the shorter chains in the long-chain acrylate esters group, information on the long-term toxicity to fish is available for Dodecyl acrylate (C12). The effects of Dodecyl acrylate to the early-life stage of fish (Danio rerio/ Zebrafish) were determined according to OECD Guideline 210. Dodecyl acrylate is a liquid with a water solubility of < 1 μg/L at 20°C. Based on the results of a range finding test the test was conducted as a limit test at the upper limit of the water solubility with a loading of 1 μg test item/L.
Due to the low solubility (< 1 μg/L) of the test item in water, Dimethylformamide (DMF) was used as solvent with a concentration of 0.050 mL DMF/L dilution water. The stock solution was continuously dosed to the dilution water in a flow through system.
For the hatchability, post hatch and overall survival and fry growth the NOEC was 1 μg/L. Therefore, the LOEC for for these parameters was determined to be > 1 μg/L. (BASF SE, 2019).
Table . Long-term toxicity to fish
Ester |
Alcohol Moiety Chain length |
Method |
Species |
NOEC[21 d] |
Reference |
Dodecyl acrylate [2156-97-0] |
C12 |
OECD 210 |
Danio rerio |
1 μg/L
|
BASF SE 2019 |
Conclusion
In accordance with column 2 Annex IX section 9.1 of Regulation (EC) No 1907/2006 (REACH), the study on long-term toxicity to fish does not need to be conducted because from the available acute data there is no indication that fish are any more sensitive than aquatic invertebrates and algae to these substances. Moreover, the absence of a long-term toxic potential to fish was demonstrated in a test with Dodecyl acrylate (C12) at a concentration above water solubility (NOEC: 1 μg/L). This result can be read across to the C12-C14 members of the category:Propenoic acid, C12-14-alkyl esters (84238-60-8) and Tetradecyl acrylate (21643-42-5).
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.