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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2019-12-04
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
1. SOFTWARE
EPISUITE v4.11
2. MODEL (incl. version number)
BIOWIN v4.10
3. SMILES: for details on the SMILES notations that have been used for QSAR, please see the attached justification.
4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
For detailed information about the used model please refer to the attached justification.
5. APPLICABILITY DOMAIN
For detailed information about the used model please refer to the attached justification.
6. ADEQUACY OF THE RESULT
For detailed information about the used model please refer to the attached justification.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
For detailed description, please see attached justification.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Glycine
EC Number:
200-272-2
EC Name:
Glycine
Cas Number:
56-40-6
Molecular formula:
C2H5NO2
IUPAC Name:
aminoacetic acid

Study design

Oxygen conditions:
aerobic/anaerobic
Inoculum or test system:
not specified
Details on inoculum:
QSAR; not applicable
Details on study design:
QSAR calculation

Results and discussion

Preliminary study:
not applicable
Details on results:
Ready Biodegradability Prediction according to BIOWIN v4.10: YES

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Remarks:
supporting QSAR calculation of glycine
Interpretation of results:
readily biodegradable
Conclusions:
According to QSAR calculation using BIOWIN v4.10, the test substance is readily biodegradable.
Executive summary:

In this study, the test substance glycine was estimated to be readily biodegradable using BIOWIN v4.10.