Registration Dossier
Registration Dossier
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EC number: 238-173-1 | CAS number: 14281-83-5
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Study period:
- 2019-12-04
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- 1. SOFTWARE
EPISUITE v4.11
2. MODEL (incl. version number)
BIOWIN v4.10
3. SMILES: for details on the SMILES notations that have been used for QSAR, please see the attached justification.
4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
For detailed information about the used model please refer to the attached justification.
5. APPLICABILITY DOMAIN
For detailed information about the used model please refer to the attached justification.
6. ADEQUACY OF THE RESULT
For detailed information about the used model please refer to the attached justification.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- For detailed description, please see attached justification.
- GLP compliance:
- no
Test material
- Reference substance name:
- Glycine
- EC Number:
- 200-272-2
- EC Name:
- Glycine
- Cas Number:
- 56-40-6
- Molecular formula:
- C2H5NO2
- IUPAC Name:
- aminoacetic acid
Constituent 1
Study design
- Oxygen conditions:
- aerobic/anaerobic
- Inoculum or test system:
- not specified
- Details on inoculum:
- QSAR; not applicable
- Details on study design:
- QSAR calculation
Results and discussion
- Preliminary study:
- not applicable
- Details on results:
- Ready Biodegradability Prediction according to BIOWIN v4.10: YES
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Remarks:
- supporting QSAR calculation of glycine
- Interpretation of results:
- readily biodegradable
- Conclusions:
- According to QSAR calculation using BIOWIN v4.10, the test substance is readily biodegradable.
- Executive summary:
In this study, the test substance glycine was estimated to be readily biodegradable using BIOWIN v4.10.
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