Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 234-759-6 | CAS number: 12031-82-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019-03-05 to 2020-01-24
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- signed, 2016-08-26
- Type of method:
- flask method
- Water solubility:
- 0.383 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- >= 192 - <= 552 d
- Temp.:
- 20 °C
- pH:
- >= 9.7 - <= 10.4
- Remarks on result:
- other: calculated based on a titanium concentration of 167 µg/L and a purity of 98 %
- Water solubility:
- 167 µg/L
- Conc. based on:
- element
- Remarks:
- Ti
- Loading of aqueous phase:
- 100 other: mg test item / L
- Incubation duration:
- >= 192 - <= 552 h
- Temp.:
- 20 °C
- pH:
- >= 9.7 - <= 10.4
- Details on results:
- The validity criteria haven´t been met.
- Conclusions:
- The water solubility of Lithium titanate at 20 °C was determined to be 0.000383 g/L.
Reference
Results of individual determinations and mean value
Flask° |
Li [µg/L] |
Ti [µg/L] |
pH |
Stirring duration [h] |
A |
1838 |
33 | 9.7 | 192 |
B | 1300 | 16 | 10.1 | 216 |
C | 1389 | 40 | 10.2 | 240 |
Mean | 1509 | 30 | - | - |
RSD | 19.1 | 41.9 | - | - |
D | 1704 | 55 | 10.4 | 360 |
E | 1966 | 161 | 9.4 | 384 |
E* | 1706 | 147 | 10.3 | 385 |
F | 1961 | 167 | 10.4 | 408 |
Mean | 1790 | 121 | - | - |
RSD | 8.2 | 51.8 | - | - |
G* | 1720 | 48 | 10.2 | 504 |
G | 1697 | 46 | 7.8 | 504.5 |
H | 2029 | 91 | 10.3 | 528 |
I | 1783 | 23 | 10.3 | 552 |
Mean | 1844 | 54 | - | - |
RSD | 8.9 | 64.3 | - | - |
Overall mean | 1714 | 68 | - | - |
Overall RSD | 13.9 | 80.2 | - | - |
RSD:
relative standard deviation in %
°
each flask was analysed 6 times (3 different dilution, double analysis)
* samples were taken again since the pH deviated significantly from
previous pH
Italic values are not included into the calculations of mean values
grey value is highest determined concentration
The measured concentrations in all flasks of all test points deviate clearly. The RSD of the all 3 weeks lies between 42 and 64 %. Overall the RSD lies at 80 %.
The relative standard deviation between the single determinations is > 15 %. The validity criteria haven ot been met. Additionally, based on the determined Titanium values, the content of Lithium is far elevated and vice versa.
As stated by the Sponsor this effect could result from mainly Lithium containing impurities in the test item which have a higher water solubility. OECD guideline 105 states that residues can have a big influence on the water solubility results.
During manufacture Lithium carbonate and Titanium dioxide are used as starting materials. Lithium carbonate has a very high water solubility (8.4 g/L). Next to Lithium carbonate also TiO (oxidises in water to TiO2) and TiO2 are known impurities (see Study No. 2016/0109/01, IUCLID section 4.1 Appearance). TiO2 has, in contrast to Lithium carbonate, a very low water solutility (≥ 0.024 - ≤ 0.172 µg/L). This impurity therefore was considered to have a neglectable influence on the titanium results. Therefore the highest titanium concentration, representing the highest possible water solubility, was used to determine a water solubility of Lithium titanate.
Since the validity critera haven´t been met, the water solubility was determined using the highest determined Titanium value of all flasks: 167 µg/L.
Therefore, the water solubility of Lithium titanate in demineralized water at 20 °C is determined to be: 0.000383 g/L
Description of key information
The water solubility of Lithium titanate at 20 °C was determined to be 0.383 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 0.383 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.