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EC number: 617-769-9 | CAS number: 858956-08-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2007-08-08 to 2007-10-26
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Food and Consumer Product Safety Authority (WMA), Den Haag, The Netherlands / National GLP Compliance Monitoring Authority, New Delhi, India
- Type of method:
- gas saturation method
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The vapour pressure of the substance was determined to be 6.9215E-6 Pa at 20 °C and 4.9113E-6 Pa at 25 °C (OECD Guideline 104, gas saturation method)
Reference
The test item transported by the nitrogen gas was adsorbed only in the first layer of silica gel in the sorbent tubes for all the tests. The second layer did not contain any test item. These results demonstrate that the sorbent material selected for the study was efficient in trapping all transported test item. A component related to the test item eluting near the retention time of IN-LXT69 (approximately 9.2 minutes) was observed in the first sorbent trap attached to the saturator columns incubated at 40, 45 and 50 °C. This component was not observed either in the method validation samples or in the extract of the fortified silica traps. In addition, test item was observed on the coated glass beads at the conclusion of the saturator column incubation indicating that the test item remained in excess for the duration of the study. Based on this data, this component related to the test item had no effect on the vapour pressure determination of the test item.
Temperature |
Vapour pressure (P) of test item [Pa] |
|||
50 mL/min |
40 mL/min |
30 mL/min |
Mean |
|
40.0 °C (313.15 K) |
2.4561E-6 |
1.4547E-6 |
2.4225E-6 |
2.1111E-6 |
45.0 °C (318.15 K) |
9.703E-7 |
1.2615E-6 |
1.0080E-6 |
1.0799E-6 |
50.0 °C (323.15 K) |
1.8020E-6 |
0.7338E-6 |
0.9723E-6 |
1.1694E-6 |
20 °C (293.15 K)*: 6.9215E-6 Pa (5.192E-8 mm Hg or Torr) |
* The vapour pressure at 20 and 25 °C presented above was calculated using the linear regression equation, which resulted from plotting VP (vapour pressure in Pa) versus temperature (1/T) in Kelvin.
Vapour Pressure at 40 °C
The duration of the main test conducted at 40 °C was approximately 28 days. The vapour pressure of the test item was determined at three different gas flow rates. The vapour pressure of the test item was 2.4561E-6, 1.4547E-6, and 2.4225E-6 Pa at 50, 40, and 30 mL/min flow rates, respectively. These results clearly indicate that the nitrogen gas was completely saturated with test item at all three flow rates for the duration of the test. The mean value of vapour pressure was 2.1111E10-6 Pa.
Vapour Pressure at 45 °C
The duration of the main test conducted at 45 °C was approximately 12 days. The vapour pressure of the test item was determined at three different gas flow rates. The vapour pressure of the test item was 9.703E-7, 1.2615E-6 and 1.0080E-6 Pa at 50, 40, and 30 mL/min carrier gas flow rate, respectively. These results clearly indicate that the carrier gas was completely saturated with test item at all three flow rates for the duration of the test. The mean value of vapour pressure was 1.0799E-6 Pa.
Vapour Pressure at 50 °C
The duration of the main test conducted at 50 °C was approximately 13 days. The vapour pressure of the test item was determined at three different gas flow rates. The vapour pressure of the test item was 1.8020E-6, 0.7338E-6 and 0.9723E-6 Pa at 50, 40, and 30 mL/min carrier gas flow rate, respectively. These results clearly indicate that the carrier gas was completely saturated with test item at all three flow rates for the duration of the test. The mean value of vapour pressure was 1.1694E-6 Pa.
Vapour Pressure at 20 and 25 °C
A vapour pressure curve was plotted using inverse value of the experimental temperature in K (1/T) on the X-axis and Log P (where P = vapour pressure in Pa) determined at that temperature) on the Y-axis. The vapour pressure of the test item at 20 and 25 °C was calculated using the slope (2613.1) and the intercept (-14.073) of the regression line (r =0.8119). The vapour pressure of the test item at 20 and 25 °C was 6.9215E-6 Pa (5.192E-8 mm Hg or Torr) and 4.9113E-6 Pa (3.684E-8 mm Hg or Torr), respectively.
Description of key information
6.9215E-6 Pa at 20 °C and 4.9113E-6 Pa at 25 °C (OECD Guideline 104, gas saturation method)
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
The vapour pressure values at 20 and 25 °C were extrapolated from the vapour pressure curve.
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