Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

n summary, under the exposure conditions employed in this study, ingestination of cupric sulfate in drinking water or feed produced hyperplasia and hyoerkeratois of the forestomach mucossia (irritant effect of the substance).
There is a copper accumulation in liver, kidney tissue and the plasma.
There was determined a NOEL value from 1000ppm for rat ant 2000ppm for mice.

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Dose descriptor:
NOAEL
1 000 mg/kg bw/day
Study duration:
subchronic
Species:
rat

Additional information

Repeated dose toxicity: via oral route - systemic effects (target organ) digestive: liver; digestive: stomach; urogenital: kidneys

Justification for classification or non-classification