Registration Dossier
Registration Dossier
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EC number: 602-997-3 | CAS number: 124495-18-7
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- other: Case report
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- other: Case report
- Title:
- Unnamed
- Year:
- 1 995
- Report date:
- 1995
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- case report
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The results given are from the Plant report on workplace exposure
- GLP compliance:
- no
Test material
- Reference substance name:
- Reference substance 001
- Cas Number:
- 124495-18-7
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- Name of the substance: XDE-795
Method
- Type of population:
- occupational
- Ethical approval:
- not specified
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- One of the formulators had two separate episodes of skin reaction on the forearms after working with the test substance. A positive reaction occured in a Buehler study with a formulation containing the test substance and fenpropimorph. It was confirmed that the latter is not a known sensitizer. The indications were that the test substance may be the cause.
Applicant's summary and conclusion
- Conclusions:
- Patch test on humans: Positive reaction
- Executive summary:
The sensitization reaction in one of the formulators was briefly discussed. The results of the patch test was positive for the test substance.
One of the formulators had two separate episodes of skin reaction on the forearms after working with the test substance. A positive reaction occured in a Buehler study with a formulation containing the test substance and fenpropimorph. It was confirmed that the latter is not a known sensitizer. The indications were that the test substance may be the cause.
The formulator patch tested positive with various substances, including the test substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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