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EC number: 263-009-0 | CAS number: 61788-81-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2005-08-01 - 2005-09-02
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Justification for read-across, see attached file.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Remarks:
- Activated sludge from the municipal sewage treatment plant in Reutlingen
- Key result
- Parameter:
- other: BOD5*100/COD
- Value:
- >= 68.1
- Sampling time:
- 14 d
- Key result
- Parameter:
- other: BOD5*100/ThOD
- Value:
- >= 81.9
- Sampling time:
- 28 d
- Key result
- Parameter:
- BOD5*100/COD
- Value:
- 68.1 other: Percent
- Remarks on result:
- other: % for 14 Days
- Remarks:
- % Biodegradation = 100 x (BOD (mg O /mg test article)/ COD (mg O /mg test article))
- Key result
- Parameter:
- BOD5*100/ThOD
- Value:
- 81.9 other: Percent
- Remarks on result:
- other: % for 28 Days
- Remarks:
- % Biodegradation = 100 x (BOD (mg O /mg test article)/ ThOD (mg O /mg test article))
- Results with reference substance:
- - Biodegradation after 14 days: 94,2 %
- Biodegradation after 28 days: 96,6 % - Interpretation of results:
- readily biodegradable
- Conclusions:
- CTO Sample 1 of Arizona Chemical achieved 82 % biodegradation in 28 days (10 days window: 63 %) in a Manometric Respirometry Test conducted according to OECD-Guideline 301 F. CTO Sample 1 is therefore readily biodegradable.
- Executive summary:
Aim: To determine the “ready biodegradability“ of Crude Tall oil.
Method:
The test is performed at a test temperature of 22 ± 2 °C under aerobic conditions in closed bottles with electrolytic oxygen supply and automatic data registration. Respirometric BOD-determination was carried out with CO2-absorption on soda lime. The test is recommended for water soluble test articles as well as insoluble and volatile test articles. The concentration of the test article was ca. 100 mg/L. The concentration of the reference article, Sodium-Benzoate, was ca. 100 mg/L.
Biodegradability is expressed as the percentage oxygen uptake (corrected for blank uptake) of the Theoretical Oxygen Demand (ThOD) or of the Chemical Oxygen Demand (COD) respectively.
Results:
Biodegradability of test article:
- Test concentration: 109,3 mg/L
- COD of the test article: 2,20 mg O2/mg test article - COD in the test flasks: 240,7 mg O2/L
- BOD in flask 1 after 28 days: 209,9 mg O2/L (including blank) - BOD in flask 2 after 28 days: 210,1 mg O2/L (including blank) - mean value: 210,0 mg O2/L (including blank) - maximum BOD-difference in flasks 1 + 2 at the end of the test (required: < 20 %): 0,1 %
- BOD in flask 3 after 28 days (inoculum blank): 6,3 mg O2/L - BOD in flask 4 after 28 days (inoculum blank): 19,5 mg O2/L - mean value inoculum blank (required: < 60 mg O2/L): 12,9 mg O2/L
- BOD in flask 6 after 28 days (abiotic degradation): 0 mg O2/L
- BODtest article - BODinoculum blank - BODtest article abiotic: 197,1 mg O2/L or 1,80 mg O2/mg test article
- Biodegradation after 14 days: 68,1 %
- Biodegradation after 28 days: 81,9 %
- 10 days window: 63,1 %
Conclusion: CTO Sample 1 of Arizona Chemical achieved 82 % biodegradation in 28 days (10 days window: 63 %) in a Manometric Respirometry Test conducted according to OECD-Guideline 301 F. CTO Sample 1 is therefore readily biodegradable.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- See justification for read-across further down.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 99
- Sampling time:
- 28 d
- Remarks on result:
- other: 2-EHA
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 90.1
- Sampling time:
- 7 d
- Remarks on result:
- other: 2-EHA
- Key result
- Parameter:
- BOD5*100/COD
- Value:
- 68.1 other: percent
- Remarks on result:
- other: Tall oil
- Key result
- Parameter:
- BOD5*100/ThOD
- Value:
- 81.9 other: pecent
- Remarks on result:
- other: Tall oil
- Executive summary:
The target UVCB, Reaction mass of Fatty acids, tall oil, 2-ethylhexanoic acid and magnesium salts is readily biodegradable and will not be classified according to CLP.
CTO Sample 1 of Arizona Chemical achieved 82 % biodegradation in 28 days (10 days window: 63 %) in a Manometric Respirometry Test conducted according to OECD-Guideline 301 F. CTO Sample 1 is therefore readily biodegradable. According to OECD guidline 301E, 2-ethylhexanoic acid is readily biodegradable with a biodegradation (28 d) > 70 % and a pass level was reached in 10-d window.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Guideline study with acceptable restrictions (e.g. non-GLP; instead of secondary effluent as recommended by the guideline, the primary effluent of a municipal sewage treatment plant was used as inoculum for this study. The authors justified this by referring (1) to the microbial concentration in the secondary effluent that was too low for the purpose of the study, and (2) to the possible presence of chemical residues within the secondary effluent that may interfere with the biological activity.)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic (adaptation not specified)
- Details on inoculum:
- INOCULUM :
- Target concentration of microbes in test solution (OECD 301 E): 10E+05 cells/L
- Origin of the inoculum : Municipal sewage treatment plant , Suomenoja , Espoo 26.05.1998
Concentration of inoculum : 1. Secondary effluent approx. 10E+03 - 10E+04 cells/ml; 2. Primary effluent approx. 10E+06 cells/ml
(Easycult TTC, Orion Diagnostica ); Inoculum 2. was used in the test to obtain sufficient microbe concentration
- Preparation of inoculum : Filtration (Schleicher & Schuell 5891 Black ribbon )
- Addition into test solution : 0.5 ml/I - Duration of test (contact time):
- 28 d
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST CONDITIONS : Incubation shaker New Brunswick G25-KLC
Continuous shaking 120 rp m
Temperature 22 ± 2 °C
Dark
Test vessels 2 I conical flasks , volume of the test solution at start 1000 ml
Free exchange of air in test vessel s
SAMPLING: DOC-samples 50 ml/sampling time and flask
Filtration of samples with Gelman Ion chromatography Acrodisc 0 .45 pm
Storage of filtered samples in -20 °C before analysis
test series:
inoculum blank (inoculum + mineral medium),
test substance (inoculum + mineral medium + test substance),
reference substance (inoculum + mineral medium + reference substance),
toxicity test (inoculum + mineral medium + test substance + reference substance) - start conditions:
mineral medium: pH 7.6, 9 mg/l O2 (= 100 %),
test substance solution: pH 7.45 - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (DOC removal)
- Value:
- 99
- Sampling time:
- 28 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 90.1
- Sampling time:
- 7 d
- Details on results:
- RS-Freetext:
Biodegradation (% relate to DOC)
0 d 2 d 5 d 7 d 14 d 28 d
test substance
(mean) 0 67.2 91.4 90.7 94.9 99.2
reference
substance 0 83.8 97.8 95.6 96.8 99.3
toxicity test 0 76.1 98.2
Biodegradation 10 d window
10 % 70 %
test substance 0.3 d 2.3 d 0.3 d - 10.3 d
reference
substance 0.2 d 1.7 d 0.2 d - 10.2 d
Conclusion:
2-ethylhexanoic acid is readily biodegradable:
- biodegradation (28 d) > 70 %
- Pass level reached in 10-d window.
Kinetic of test substance (in %):
= 67 after 2 day(s)
= 91 after 5 day(s)
= 91 after 7 day(s)
= 95 after 14 day(s)
Kinetic of control substance (in %):
= 84 after 2 day(s)
= 98 after 5 day(s)
Degradation products: not measured - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
Referenceopen allclose all
Abiotic
and adsorption tests were poisoned with 15 mg/l Na azide to prevent
bioactivity. The dosage was not sufficient to stop microbial growth
in test vessels, and so the tests were interrupted as the preliminary
results showed at the same time that these factors are not likely
to interfere the biodegradation of the test substance.
test has been performed by Ekolab Environmental Oy (sponsor: Finnish
Chemicals Oy)
Description of key information
The information on biodegradation of the substance is based on read across from Tall oil and 2-ethylhexanoic acid and reveals readily. Furthermore, the source substances contain higher or similar concentrations of the constituents used for read across compared to the target substance. There are no scientific reasons indicating that the constituents of the substance can interact in a way that will influence the toxicological/ecotoxicological properties of the substance.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
CTO Sample 1 of Arizona Chemical achieved 82 % biodegradation in 28 days (10 days window: 63 %) in a Manometric Respirometry Test conducted according to OECD-Guideline 301 F. CTO Sample 1 is therefore readily biodegradable. According to OECD guidline 301E, 2-ethylhexanoic acid is readily biodegradable with a biodegradation (28 d) > 70 % and a pass level was reached in 10-d window.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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