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Diss Factsheets
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EC number: 446-640-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
- Report date:
- 2003
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 92/69/EC, C.4-A 28-day DOC die-away test
- GLP compliance:
- yes
Test material
Constituent 1
Study design
- Inoculum or test system:
- other: aerobic activated sludge from a wastewater treatment plant treating predominantly domestic wastewater
Reference substance
- Reference substance:
- other: Sodium benzoate
Results and discussion
% Degradation
- Parameter:
- other: See report
- Value:
- ca. 2.5
- St. dev.:
- 0
- Sampling time:
- 28 d
- Remarks on result:
- other: see report
- Details on results:
- Points of degradation plot (test substance):
0 % degradation after 7 d
0 % degradation after 14 d
1 % degradation after 21 d
2.5 % degradation after 28 d
BOD5 / COD results
BOD5 / COD
- Parameter:
- COD
- Value:
- ca. 34 mg O2/g test mat.
- Results with reference substance:
- Points of degradation plot (reference substance):
98.5 % degradation after 7 d
99.5 % degradation after 14 d
99.5 % degradation after 21 d
99 % degradation after 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- 3.1 DEGRADATION OF THE TEST ITEM
The results are presented in Tables 1 and 2, and in Figures 1 and 2.
In the test flasks containing the test item and activated sludge (inoculum] the DOC
concentrations (dissolved organic carbon corrected for the DOC of the inoculum controls)
varied between 33.1 and 34.6 mg/L over the exposure period of 28 days and were not
significantly different from the initial DOC concentrations of 34.0 and 34.1 mg/L measured on
Day 0. Expressed as percentage DOC removal, values in the range from -2 to 3% were
noted. Therefore, ucb 22060 was found to be not biodegradable under the conditions of the
test.
Abiotic control:
The results are presented in Table 1 and in Figure 1.
In the abiotic control, containing the test item and poisoned medium, the DOC
concentrations varied from 35.8 to 36.4 mg/L over the exposure period of 28 days and were
not significantly different from the initial DOC concentration of 34.9 mg/L measured at Day O.
Thus, no abiotic degradation occurred under the conditions of the test.
3.2 DEGRADATION OF THE REFERENCE ITEM
The results are presented in Tables 1 and 2, and in Figures 1 and 2,
In the procedure controls containing the reference item sodium benzoate and activated
sludge (inoculum), sodium benzoate was completely biodegraded within 7 days of exposure,
confirming suitability of the activated sludge.
3.3 DEGRADATION IN THE TOXICITY CONTROL
The results are presented in Tables 1 and 2, and in Figures 1 and 2.
In the toxicity control, containing the test item (corresponding to 57% of total DOC), the
reference item (corresponding to 43% of total DOC) and activated sludge (inoculum), the
initial DOC concentration (corrected for the DOC of the inoculum control) of 67.6 mg/L
measured on Day O decreased to 36.0 mg/L on Day 14. Biodegradation amounted to 47°4
within 14 days of exposure. Thus, according to the test guidelines the test item can be
assumed to not be inhibitory to activated sludge because degradation was >35Y0 within
14 days. - Executive summary:
The test item ucb 22060 was investigated for its ready biodegradability in a “28-Day DOC
Die-Away Test” according to EU Commission Directive 92/69 EEC, C.4-A (1992) and OECD
Guideline for Testing of Chemicals, No. 301 A (1992).
In the test flasks containing the test item ucb 22060 and activated sludge (inoculum) the
concentrations of dissolved organic carbon (DOC) were not significantly different from the
initial DOC concentrations measured on Day O. Therefore, ucb 22060 was found to be not
biodegradable under the conditions of the test.
In the abiotic control, containing the test item and poisoned mineral medium, no degradation
was noted after 28 days of exposure (based on DOC measurements).
The reference item sodium benzoate was completely biodegraded within 7 days of exposure,
confirming suitability of the activated sludge.
In the toxicity control, containing the test item, the reference item sodium benzoate and
activated sludge (inoculum), the initial DOC decreased by 47% within 14 days of exposure.
Thus, according to the test guidelines the test item can be assumed to be not inhibitory to
activated sludge because degradation was >35Y0within 14 days.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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