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EC number: 265-967-5 | CAS number: 65894-76-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09 November 2017 to 13 November 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 2008
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.005 Pa
- Conclusions:
- Under the conditions of this study, the vapour pressure of the test material has been determined to be 5.0 x 10^-3 Pa at 25 °C.
- Executive summary:
The vapour pressure of the test material was determined in accordance with the standardised guidelines OECD 104 and EU Method A.4, under GLP conditions.
The vapour pressure was determined using a vapour pressure balance. The temperature of the sample was controlled electronically.
The test material did not change in appearance under the conditions used in the determination. A total of 10 runs were completed for the main sequence. Equilibrium with regard to vapour pressure was assessed to have been reached over the final 7 runs. Thus the final 7 runs have been used to calculate the definitive vapour pressure value for the test material.
Under the conditions of this study, the vapour pressure of the test material has been determined to be 5.0 x 10^-3 Pa at 25 °C.
Reference
Run 4 Table1: Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapor Pressure (Pa) |
Log10Vp |
|||||||
39 |
312.15 |
0.003203588 |
12.28 |
1.228E-08 |
0.017047786 |
-1.768332012 |
|||||||
40 |
313.15 |
0.003193358 |
12.08 |
1.208E-08 |
0.016770135 |
-1.775463444 |
|||||||
41 |
314.15 |
0.003183193 |
13.18 |
1.318E-08 |
0.018297217 |
-1.737614968 |
|||||||
42 |
315.15 |
0.003173092 |
13.98 |
1.398E-08 |
0.019407822 |
-1.712023207 |
|||||||
43 |
316.15 |
0.003163056 |
14.98 |
1.498E-08 |
0.020796078 |
-1.682018565 |
|||||||
44 |
317.15 |
0.003153082 |
16.77 |
1.677E-08 |
0.023281056 |
-1.632997316 |
|||||||
45 |
318.15 |
0.003143171 |
18.37 |
1.837E-08 |
0.025502266 |
-1.593421222 |
|||||||
46 |
319.15 |
0.003133323 |
20.57 |
2.057E-08 |
0.028556430 |
-1.544296087 |
- A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistical data using an unweighted least squares treatment.
Slope: -3.34 x 10^3
Standard error in slope: 286
Intercept: 8.91
Standard error in intercept: 0.907
- The results obtained indicate the following vapour pressure relationship:
Log10 (Vp (Pa)) = -3.34 x 10^3/temp(K) + 8.91
- The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.30.
Run 5 Table2: Vapor Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapor Pressure (Pa) |
Log10Vp |
39 |
312.15 |
0.003203588 |
11.88 |
1.188E-08 |
0.016492484 |
-1.782713938 |
40 |
313.15 |
0.003193358 |
12.38 |
1.238E-08 |
0.017186612 |
-1.764809734 |
42 |
315.15 |
0.003173092 |
14.48 |
1.448E-08 |
0.020101950 |
-1.696761817 |
43 |
316.15 |
0.003163056 |
15.97 |
1.597E-08 |
0.022170451 |
-1.654225463 |
44 |
317.15 |
0.003153082 |
16.27 |
1.627E-08 |
0.022586928 |
-1.646142826 |
45 |
318.15 |
0.003143171 |
19.37 |
1.937E-08 |
0.026890523 |
-1.570400758 |
46 |
319.15 |
0.003133323 |
21.47 |
2.147E-08 |
0.029805861 |
-1.525698334 |
- A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 5 gives the following statistical data using an unweighted least squares treatment:
Slope: -3.61 x 10^3
Standard error in slope: 292
Intercept: 9.78
Standard error in intercept: 0.925
- The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3.61 x 10^3/temp(K) + 9.78
The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -2.34.
Run 6 Table 3: Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapor Pressure (Pa) |
Log10Vp |
39 |
312.15 |
0.003203588 |
12.38 |
1.238E-08 |
0.017186612 |
-1.764809734 |
40 |
313.15 |
0.003193358 |
12.18 |
1.218E-08 |
0.016908960 |
-1.771883090 |
41 |
314.15 |
0.003183193 |
13.78 |
1.378E-08 |
0.019130170 |
-1.718281161 |
42 |
315.15 |
0.003173092 |
15.08 |
1.508E-08 |
0.020934903 |
-1.679129037 |
43 |
316.15 |
0.003163056 |
15.18 |
1.518E-08 |
0.021073729 |
-1.676258607 |
44 |
317.15 |
0.003153082 |
16.77 |
1.677E-08 |
0.023281056 |
-1.632997316 |
45 |
318.15 |
0.003143171 |
19.37 |
1.937E-08 |
0.026890523 |
-1.570400758 |
46 |
319.15 |
0.003133323 |
19.77 |
1.977E-08 |
0.027445825 |
-1.561523709 |
- A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 6 gives the following statistical data using an unweighted least squares treatment:
Slope: -3.19 x 10^3
Standard error in slope: 270
Intercept: 8.43
Standard error in intercept: 0.855
- The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3.19 x 10^3/temp(K) + 8.43
- The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.26.
Run 7 Table 4: Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapor Pressure (Pa) |
Log10Vp |
39 |
312.15 |
0.003203588 |
12.48 |
1.248E-08 |
0.017325437 |
-1.761315793 |
40 |
313.15 |
0.003193358 |
12.58 |
1.258E-08 |
0.017464263 |
-1.757849738 |
41 |
314.15 |
0.003183193 |
13.18 |
1.318E-08 |
0.018297217 |
-1.737614968 |
42 |
315.15 |
0.003173092 |
12.98 |
1.298E-08 |
0.018019565 |
-1.744255686 |
43 |
316.15 |
0.003163056 |
15.28 |
1.528E-08 |
0.021212555 |
-1.673407024 |
44 |
317.15 |
0.003153082 |
16.67 |
1.667E-08 |
0.023142231 |
-1.635594779 |
45 |
318.15 |
0.003143171 |
18.87 |
1.887E-08 |
0.026196394 |
-1.581758479 |
46 |
319.15 |
0.003133323 |
21.37 |
2.137E-08 |
0.029667035 |
-1.527725857 |
- A plot of Log1 0(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 7 gives the following statistical data using an unweighted least squares treatment:
Slope: -3.42 x 10^3
Standard error in slope: 457
Intercept: 9.17
Standard error in intercept: 1.45
- The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3.42 x 10^3/temp(K) + 9.17
- The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.31.
Run 8 Table 5: Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapor Pressure (Pa) |
Log10Vp |
39 |
312.15 |
0.003203588 |
11.88 |
1.188E-08 |
0.016492484 |
-1.782713938 |
40 |
313.15 |
0.003193358 |
13.98 |
1.398E-08 |
0.019407822 |
-1.712023207 |
41 |
314.15 |
0.003183193 |
12.68 |
1.268E-08 |
0.017603089 |
-1.754411125 |
42 |
315.15 |
0.003173092 |
14.58 |
1.458E-08 |
0.020240775 |
-1.693772855 |
43 |
316.15 |
0.003163056 |
14.68 |
1.468E-08 |
0.020379601 |
-1.690804323 |
44 |
317.15 |
0.003153082 |
16.47 |
1.647E-08 |
0.022864580 |
-1.640836780 |
45 |
318.15 |
0.003143171 |
18.67 |
1.867E-08 |
0.025918743 |
-1.586386061 |
46 |
319.15 |
0.003133323 |
20.37 |
2.037E-08 |
0.028278779 |
-1.548539350 |
A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 8 gives the following statistical data using an unweighted least squares treatment:
Slope: -3.09 x 10^3
Standard error in slope: 416
Intercept: 8.12
Standard error in intercept: 1.32
- The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3.09 x 10^3/temp(K) + 8.12
- The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.25.
Run 9 Table 6: Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapor Pressure (Pa) |
Log10Vp |
39 |
312.15 |
0.003203588 |
11.58 |
1.158E-08 |
0.016076007 |
-1.793821819 |
40 |
313.15 |
0.003193358 |
12.28 |
1.228E-08 |
0.017047786 |
-1.768332012 |
41 |
314.15 |
0.003183193 |
12.98 |
1.298E-08 |
0.018019565 |
-1.744255686 |
42 |
315.15 |
0.003173092 |
14.38 |
1.438E-08 |
0.019963124 |
-1.699771493 |
43 |
316.15 |
0.003163056 |
15.08 |
1.508E-08 |
0.020934903 |
-1.679129037 |
44 |
317.15 |
0.003153082 |
16.37 |
1.637E-08 |
0.022725754 |
-1.643481699 |
45 |
318.15 |
0.003143171 |
17.77 |
1.777E-08 |
0.024669313 |
-1.607842951 |
46 |
319.15 |
0.003133323 |
20.27 |
2.027E-08 |
0.028139953 |
-1.550676630 |
- A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 9 gives the following statistical data using an unweighted least squares treatment:
Slope: -3.35 x 10^3
Standard error in slope: 170
Intercept: 8.93
Standard error in intercept: 0.540
- The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3.35 x 10^3/temp(K) + 8.93
- The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.31.
Run 10 Table 7: Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapor Pressure (Pa) |
Log10Vp |
39 |
312.15 |
0.003203588 |
11.78 |
1.178E-08 |
0.016353658 |
-1.786385088 |
40 |
313.15 |
0.003193358 |
12.58 |
1.258E-08 |
0.017464263 |
-1.757849738 |
41 |
314.15 |
0.003183193 |
13.08 |
1.308E-08 |
0.018158391 |
-1.740922635 |
42 |
315.15 |
0.003173092 |
13.98 |
1.398E-08 |
0.019407822 |
-1.712023207 |
43 |
316.15 |
0.003163056 |
15.18 |
1.518E-08 |
0.021073729 |
-1.676258607 |
44 |
317.15 |
0.003153082 |
16.97 |
1.697E-08 |
0.023558708 |
-1.627848536 |
45 |
318.15 |
0.003143171 |
18.57 |
1.857E-08 |
0.025779918 |
-1.588718475 |
46 |
319.15 |
0.003133323 |
20.27 |
2.027E-08 |
0.028139953 |
-1.550676630 |
- A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 10 gives the following statistical data using an unweighted least squares treatment.
Slope: -3.40 x 10^3
Standard error in slope: 192
Intercept: 9.10
Standard error in intercept: 0.607
- The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3.40 x 10^3/temp(K) + 9.10
- The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.31.
Summary of Results
- The values of vapour pressure at 25 °C extrapolated from each graph are summarised in the following table:
Table 8: Summary of Vapour Pressure Data
Run |
Log10[Vp(25 ºC)] |
4 |
-2.30 |
5 |
-2.34 |
6 |
-2.26 |
7 |
-2.31 |
8 |
-2.25 |
9 |
-2.31 |
10 |
-2.31 |
Mean |
-2.30 |
Vapour Pressure |
5.02 x 10-3Pa |
Discussion
- The test material did not change in appearance under the conditions used in the determination.
- A total of 10 runs were completed for the main sequence. Equilibrium with regard to vapour pressure was assessed to have been reached over the final 7 runs. Thus the final 7 runs have been used to calculate the definitive vapour pressure value for the test material.
- The results may represent rounded values obtained by calculations based on the exact raw data.
Description of key information
Under the conditions of this study, the vapour pressure of the test material has been determined to be 5.0 x 10^-3 at 25 °C.
Key value for chemical safety assessment
- Vapour pressure:
- 0.005 Pa
- at the temperature of:
- 25 °C
Additional information
The vapour pressure of the test material was determined in accordance with the standardised guidelines OECD 104 and EU Method A.4, under GLP conditions.
The vapour pressure was determined using a vapour pressure balance. The temperature of the sample was controlled electronically.
The test material did not change in appearance under the conditions used in the determination. A total of 10 runs were completed for the main sequence. Equilibrium with regard to vapour pressure was assessed to have been reached over the final 7 runs. Thus the final 7 runs have been used to calculate the definitive vapour pressure value for the test material.
Under the conditions of this study, the vapour pressure of the test material has been determined to be 5.0 x 10^-3 at 25 °C.
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