Registration Dossier
Registration Dossier
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EC number: 700-162-9 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no adverse effect observed
- Study duration:
- subacute
- Species:
- rat
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Additional information
Short description of key information:
WS400128 was tested in a Combined Repeated Dose Oral (Gavage)
Toxicity Study with the Reproduction/Developmental Toxicity Screening
Test (OECD 422) at dose levels of 0 (vehicle control), 100, 300, 1000
mg/kg bw/day. The NOAEL regarding fertility was derived at 1000
mg/kg/day.
In a 90 day repeated dose study the NOAEL was derived at 1000 mg/kg/day;
no effects were observed in reproduction organs and tissues.
Effects on developmental toxicity
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no adverse effect observed
- Species:
- rat
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Based on the available results classification of WS400128 regarding reprotoxic or developmental toxicity according to European classification rules [REGULATION (EC) 1272/2008] is not necessary.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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