Registration Dossier
Registration Dossier
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EC number: 231-968-4 | CAS number: 7782-89-0
Endpoint summary
Administrative data
Description of key information
Lithium amide is regarded as corrosive to the skin.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study need not be conducted because the available information indicates that the criteria are met for classification as corrosive to the skin or irritating to eyes
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Link to relevant study records
- Endpoint:
- eye irritation: in vitro / ex vivo
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study need not be conducted because the available information indicates that the criteria are met for classification as corrosive to the skin or irritating to eyes
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
In accordance with column 2 of REACH Regulation (EC) No 1907/2006, Annex VII, section 8.2, a study for skin or eye irritation does not need to be conducted if the available information indicates that the criteria are met for classification as corrosive to the skin or irritating to eyes.
According to the Hommel handbook, the substance causes severe skin burns and eye damage. There is also a risk of irreversible damage of the eyes (e.g. blindness). Lung and larynx edema could also occur even with a delay of 2 days.
Sax's Dangerous Properties of Industrial Materials further describes the substance as powerful irritant to skin, eyes and mucous membrane.
Based on the above data and the ability of the test substance to react with moisture to corrosive ammonia gas and lithium hydroxide, tests on eye and skin irritation were waived.
Justification for classification or non-classification
Based on the above results, lithium amide is regarded as skin corrosive (Cat. 1 (H314) according to Regulation (EC) No 1272/2008 (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
