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Diss Factsheets
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EC number: 202-190-2 | CAS number: 92-79-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1996
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: according to OECD 301B (Sturm test); experimental part equivalent to GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- GLP compliance:
- no
- Remarks:
- experimental part acc. to GLP standards but no quality control, sample storage and GLP certificate
Test material
- Reference substance name:
- 3-hydroxy-4'-methoxy-2-naphthanilide
- EC Number:
- 202-190-2
- EC Name:
- 3-hydroxy-4'-methoxy-2-naphthanilide
- Cas Number:
- 92-79-5
- Molecular formula:
- C18H15NO3
- IUPAC Name:
- 3-hydroxy-4'-methoxy-2-naphthanilide
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Origin of inoculum: municipal sewage treatment plant Frankfurt-Sindlingen, Germany
Source: washed activated sludge of municipal sewage treatment
Preparation of suspension: activated sludge sediment centrifugated twice and resuspended in de-ionized water
Used quantity of inoculum: 10 ml/L suspended sludge
Pretreatment: acc. to guideline; pre-aeration of supernatant for 5 days to deactivate carbon dissolved in activated sludge
Preconditions: not pre-adapted to the test substance and the reference material - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 22.57 mg/L
- Based on:
- test mat.
- Initial conc.:
- 22.93 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- Due to the low solubility of the tested substance no stock solution was prepared. The tested substance was added directly to the test flasks.
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- The value %Degr. is the mean value of two test flasks with two different initial concentrations of the test substance (see section: initial test substance concentration);
The %Degr. value is based on the ratio of determined CO2 formation and the theoretical CO2 formation.
Determinded values were corrected by control values from a blank test performed without any testing substance.
The CO2-evolution of the blank test was below 50 mg/L after 28 days.
BOD5 / COD results
- Results with reference substance:
- The reference test using benzoic acid sodium salt as reference substance provided a CO2-evolution of more than 60% within 14 days (mean value of 2 tests in 2 test flasks). The %Degr. value is based on the ratio of determined CO2 formation and the theoretical CO2 formation.
The CO2-evolution of the blank test was below 50 mg/L after 28 days.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test item is not (readily) biodegradable.
- Executive summary:
The ready biodegradability of Naphtol AS-RL was tested using a non adapted activated sludge in the CO2 evolution test for a period of 28 days according to OECD guideline 301 B.
No (ready) biodegradation was found (%Degr. = 0)
The validity criteria of the guideline are fulfilled.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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