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Diss Factsheets
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EC number: 940-803-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Justification for type of information:
- Not possible to isolate from water without decomposition, so commercial product used for testing
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method)
- Version / remarks:
- The water solubility of the two phosphate esters in Thetawet FS-8250 were relatively low: 6829 mg/L for the monoester and 683 mg/L for the di-ester (ref. ICT-AR07082017); in order to ensure both the components were adequately soluble in the aqueous phase, 0.05% (actives) solutions were selected for the study
- GLP compliance:
- no
- Type of method:
- slow-stirring method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Thetawet FS-8250 is a 28% actives aqueous emulsion, water dispersible, low foam anionic fluorosurfactant
The active components are ammonium salts of [Mono & Di] 2-(Perfluorohexyl)ethyl-Phosphate. Found at ca. 10% and 18% respectively in the final product
Lot number: w17061205
Manufacturing date: 6/12/2017
Manufacturing Location: 103 Walnut Grove Road, Cartersville, GA 30120 - Analytical method:
- liquid chromatography
- Key result
- Type:
- Pow
- Partition coefficient:
- >= -1.78 - <= 0.83
- Temp.:
- 21 °C
- pH:
- 8
- Remarks on result:
- other: The lower value is associted with the mono species and the higher value with the bis species
- Details on results:
- The product mixture is a stable aqueous emulsion (28% actives) with limited water solubility; the two primary components have different water solubilities (ref. ICT-AR07082017), and as a result they partition differently between Octanol and water phases; the mono-ester favored the aqueous phase, whereas the di-ester largely moved to the octanol phase.
Therefore, the analyses for the Pow concentrations were determined via analysis of different phases for the two; i.e., the mono-ester was quantified in the Octanol phase and the di-ester in the aqueous phase and those values were used to determine the concentration in the other phase by difference; the expected concentrations of each were calculated as if all the component had partitioned into a single phase; after analysis the difference between the two would be used to calculate the ratio
Reference
Description of key information
This substance is a product by process; a mixed phosphate ester from 2-(Perfluorohexyl)ethanol
The active components are ammonium salts of [Mono & Di] 2-(Perfluorohexyl)ethyl-Phosphate
It is a 28% actives aqueous emulsion. The ratio of the above products is ca. 1 : 2 respectively. In the formulated emulsion, analytical results typically fall around 10% for the mono-ester and 20% for the di-ester.
It was opted to conduct the Kow study on the product mixture for two reasons
1.The substance is a product by process, so the two component mixture is the delivered product
2. Manipulation of the product through drying or separation can alter the product
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.081
- at the temperature of:
- 21 °C
Additional information
Pow of Mono[2-(perfluorohexyl)ethyl] Phosphate was determined as -1.78 +/- 0.1 and the Pow of Bis[2-(perfluorohexyl)ethyl] Phosphate was determined as 0.83 +/- 0.05. The bis component is the majority component in the reaction mix. Conversion of the Pow to Log Pow has given the reported value.
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