Registration Dossier
Registration Dossier
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EC number: 271-816-4 | CAS number: 68609-04-1 The complex combination of hydrocarbons produced by the distillation of products from the air oxidation of cyclohexane after removal of acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C12 and boiling in the range of approximately 172°C to 324°C (342°F to 615°F).
Endpoint summary
Administrative data
Description of key information
No mortality in an acute oral limit dose test (OECD guideline 423- acute toxic class method). LD50 > 2000 mg/kg bw.
Key value for chemical safety assessment
Additional information
Acute oral:
In an acute oral limit dose test (OECD guideline 423- acute toxic class method) in Wistar rats, no mortality was observed following the gavage of 2000 mg/kg bw (BASF AG, 1998). Furthermore no clinical signs were observed in males and in females apart of reversible impaired general state, dyspnoea, staggering and piloerection.
Inhalation:
No valid acute inhalation assay with an enriched and characterized aerosol exposure is available. Though the available inhalation risk assays with atmospheres saturated with vapors of the volatile components of a test substance did not identify mortality or signs of systemic toxicity in rats (BASF AG, 1962/1963).
Dermal:
No valid acute dermal assay is available. In a rather uncommon assay shaved rats were placed with their bellies for 4 hours in a tub filled with 10-15 g of the undiluted test substance (BASF AG, 1998). No mortalities and no symptoms of systemic toxicity were observed. Although no conclusions on dose etc. can be made.
Justification for classification or non-classification
No classification since no mortality was observed in an acute oral limit dose test (OECD guideline 423- acute toxic class method) at a dose level of 2000 mg/kg bw.
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