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EC number: 211-995-8 | CAS number: 734-32-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1995
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- Deviations:
- no
- Principles of method if other than guideline:
- Not relevant
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- - Type: mixed population of aquatic microorganisms (activated sewage sludge)
- Origin: municipal sewage treatment plant, predominantly dealing with domestic sewage
- Date of collection: on the day of the start of the experiment
Pre-treatment of the inoculum:
- The sewage sludge was kept under aerobic conditions
- Approximately 2 hours before the start of the incubation, aeration was discontinued and the sludge was allowed to sediment
- The inoculum was obtained from the supernatant - Duration of test (contact time):
- 28 d
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Details on study design:
- TEST CONDITIONS:
PREPARATION OF THE STOCK SOLUTIONS::
- 1 g sodium acetate (reference substance) was dissolved in 1000 mL aqua dest. (290.1 mg/L TOC/289.8 mg/L DOC)
- 200.2 mg test substance was dissolved in 2 L aqua dest. (78.7 mg/L TOC/76.5 mg/L DOC)
- Since the difference in TOC and DOC of the test solutions did not exceed 10%, all test solutions were prepared by using the respective unfiltered stock solutions
PREPARATION OF THE TEST SOLUTION:
- Sodium acetate: 69 mL of the stock solution, 15 mL nutrient solution and 915.5 mL aqua dest.
- Test item + sodium acetate: 69 mL of the sodium acetate stock solution + 254 mL of the test item stock solution + 15 mL nutrient solution + 661.5 mL aqua dest.
- Test item: 254 mL of the stock solution, 15 mL nutrient solution and 730.5 mL aqua dest.
ADDITION OF THE INOCULUM:
- The test and reference substance solutions were measured for pH (7.5); they were not pH-adjusted
- 0.5 mL of the inoculum was added to each test solution as weil as the reference solution; additionally, a blank containing the nutrient solutions, aqua dest. and the inoculum was prepared
- Triplicate 2-litre glass beakers were used for the blank and for the test substance solution; the reference and the toxicity control solutions were each incubated in one 2-litre grass beaker
EXPOSURE CONDITIONS:
- Final test concentration: approx. 20 mg DOC/1000 mL
- Mixing : 1 magnetic stirrer per test vessel; constant stirring in darkness
- Incubation time : 28 days
- Incubation temperature : 23 ± 1 °C
- pH value of test solutions: 7.5 (not adjusted) - Reference substance:
- acetic acid, sodium salt
- Remarks:
- Purity not specified
- Parameter:
- % degradation (DOC removal)
- Value:
- 16
- Sampling time:
- 8 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 82
- Sampling time:
- 15 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 89
- Sampling time:
- 22 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 85
- Sampling time:
- 28 d
- Details on results:
- In the toxicity control, the reference compound sodium acetate plus the test item was degraded to 96 % within 28 days.
- Results with reference substance:
- The reference compound sodium acetate was degraded to 99 % on day 5.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Within 28 days the substance was degraded to 85%. The reference compound was degraded to 99% on day 5. In the toxicity control, the reference compound sodium acetate plus the test item was degraded to 96 % within 28 days.
- Executive summary:
The study on ready biodegradability was conducted in agreement with the test guideline of the OECD, No. 301 E. The substance was incubated in aqueous solution including nutrients with microorganisms from a municipal sewage treatment plant for 28 days. The nutrient solution contained phosphates, ammonium chloride, vitamins and trace elements. The test concentration was 20 mg/L as dissolved organic carbon (DOC) for the test substance. Additionally, a reference substance (sodium acetate) was tested at the same DOC concentration and according to the same procedure in order to verity the viability and activity of the degrading microorganisms. Furthermore, one flask containing the test substance and the reference substance, in each case 20 mg/L as DOC, total 40 mg/L as DOC, was tested as a toxicity contral. Three additional vessels without any test or reference substance were used as blank (control). The biological degradation of the test and reference substances was evaluated by the decrease of DOC in the solutions. DOC was analysed on days 1, 2, 5, 8, 15, 22, 28 and 29. Within 28 days the substance was degraded to 85%. The reference compound was degraded to 99% on day 5. In the toxicity control, the reference compound sodium acetate plus the test item was degraded to 96 % within 28 days. Therefore the substance has to be classified as "Readily biodegradable".
Reference
Description of key information
The substance showed 85% degradation within 28 days. The reference compound was degraded to 99% . In the toxicity control, the reference compound sodium acetate plus the test item was degraded to 96 % within 28 days.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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