Registration Dossier
Registration Dossier
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EC number: 262-038-6 | CAS number: 60047-17-8
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 1 150 mg/kg bw
- Quality of whole database:
- Klimisch 4 studies. Acceptable for classification.
Additional information
Two klimisch 4 studies have been used to fill this endpoint. The data obtained for both studies are very similar with regard to the toxicity observed. The Moreno study conducted in 1977 has a LD50 of ca. 1.15 mg/kg and the personnel communication is a 1 page document which indicates that the LD50 for females is 1343 mg/kg, and the LD50 for males is 2623 mg/kg. Therefore the worse case scenario is the Moreno study and this will be used for classification purposes.
Justification for selection of acute toxicity – oral endpoint
Two klimisch 4 studies have been used to fill this endpoint.
Justification for classification or non-classification
Moreno study for acute oral toxicity indicates that the LD50 is 1.15 mg.kg.
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