Registration Dossier
Registration Dossier
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EC number: 608-671-7 | CAS number: 318465-73-5
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study according to international accepted guidelines but not GLP compliant.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- ASTM E 537-12
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- thermal analysis
- Remarks:
- differential scanning calorimetry
Test material
- Reference substance name:
- 2-[(2-{[4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl]methoxy}ethyl)carbamoyl]benzoic acid
- EC Number:
- 608-671-7
- Cas Number:
- 318465-73-5
- Molecular formula:
- C28H29ClN2O8
- IUPAC Name:
- 2-[(2-{[4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl]methoxy}ethyl)carbamoyl]benzoic acid
- Test material form:
- solid: crystalline
- Details on test material:
- Test item: amlodipine phthalamidic acid
Batch No.: K51217N
Physical state: crystalline powder
Colour: light yellow
Storage: at 15-30 °C, protected from light and wet
Constituent 1
Results and discussion
Melting / freezing point
- Melting / freezing pt.:
- 169 °C
- Atm. press.:
- 99.8 kPa
- Decomposition:
- yes
- Decomp. temp.:
- > 160 °C
- Sublimation:
- no
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
