Registration Dossier
Registration Dossier
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EC number: 268-667-2 | CAS number: 68133-24-4
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
The similar substance 1 was tested in a plate incorporation assay (with and without rat S9) and a pre-incubation assay (with and without hamster S9 with FMN) in Salmonella typhimurium TA98, TA100, TA1535 and TA1537 as well as in E. coli WP2 uvr A. Limited cytotoxicity was observed and the number of revertants in both assays was within control ranges. Therefore it is concluded that the substance does not induce mutations in bacterial cells (BASF 1999).
Moreover a prediction with the QSAR dyes RC 2.0 Developed by Milano Chemometrics and QASR research group Dept. Earth and Environmental Science, University Milano was performed on Reactive Blue 171, and the substance resulted not classified.
Read across is discussed in section 13
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Additional information
Justification for classification or non-classification
Based on the information available and in a weight of evidence approach the substance does not need to be classified for mutagenicity according to Regulation ((EC) No 1272/2008 (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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