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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2016-08-03 to 2016-08-05
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: ISO 13320:2009 / CIPAC MT 187
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of particle tested:
other: Sample sieved, fraction <2000um tested
Type of distribution:
mass based distribution
Specific details on test material used for the study:
Batch CP2684
Mass median aerodynamic diameter:
266.39 µm
Geometric standard deviation:
0.3
Percentile:
D10
Mean:
23.523 µm
St. dev.:
0.4
Percentile:
D50
Mean:
154.575 µm
St. dev.:
0.3
Percentile:
D90
Mean:
376.811 µm
St. dev.:
0.4
Conclusions:
Manual sieve analysis indicated that 85.1 % by weight of the sample had a particle size of < 2000 µm. The analysis was conducted using the small volume (wet) module (SVM) with kerosene as the dispersant. The results of the laser diffraction test conducted to determine the particle size of the fraction of sample < 2000 µm was that the sample had a MMAD of 266.39 um.
Executive summary:

Manual sieve analysis indicated that 85.1 % by weight of the sample had a particle size of <2000 um. The analysis was conducted using the small volume (wet) module (SVM) with kerosene as the dispersant. The results of the laser diffraction test conducted to determine the particle size of the fraction of sample <2000 um are summarised below:

 Particle Size Analysis using small volume (wet) module (SVM)  Average (um)
 Volume weighted mean  180.314
 Median (d.50)  154.575
 Mode  221.269
 Mass Median Aerodynamic Diameter (MMAD)  226.390
 10% of material is <  23.523
 50% of material is <  154.575
 90% of material is <  376.811
 volume of sample < 10.00 um  3.55%

Description of key information

nual sieve analysis indicated that 85.1 % by weight of the sample had a particle size of < 2000 um.

Manual sieve analysis indicated that 85.1 % by weight of the sample had a particle size of < 2000 um.

The MMAD determined by laser diffraction was 266.390 um.

The analysis was conducted using the small volume (wet) module (SVM) with kerosene as the dispersant. The results of the laser diffraction test conducted to determine the particle size of the fraction of sample < 2000 um gave an MMAD of 266.39 um.

Additional information

 Particle Size Analysis using small volume (wet) module (SVM)  Average (um)
 Volume weighted mean  180.314
 Median (d.50)  154.575
 Mode  221.269
 Mass Median Aerodynamic Diameter (MMAD)  226.390
 10% of material is <  23.523
 50% of material is <  154.575
 90% of material is <  376.811
 volume of sample < 10.00 um  3.55%