Registration Dossier
Registration Dossier
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EC number: 210-890-4 | CAS number: 625-36-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound: no data available
Hydrolysis product 3-chloropropionic acid: with high probability acutely harmful to algae
Hydrolysis product HCl: Acutely very toxic for aquatic algae (pH dependent)
Key value for chemical safety assessment
Additional information
No data for the parent 3-chloropropionyl chloride (CAS 625-36-5) are available. However, the parent compound 3-chloropropionyl chloride (CAS 625-36-5) rapidly hydrolyses in contact with water and forms 3-chloropropionic acid (107-94-8) and HCL (CAS 7647 -01 -0). Therefore, the toxicity to aquatic green algae and cyanobacteria will be assessed based on the information available for the hydrolysis products 3-chloropropionic acid and HCl.
Parent compound 3-chloropropionyl chloride(CAS 625-36-5): No data available.
Hydrolysis product 3-chloropropionic acid (CAS 107-94-8):
In a key study conducted according to OECD 201 Guideline a 72-h ErC10 was determined to be 10.1 mg/L. This static study was performed with Desmodesmus subspicatus (nominal, analytically verified, ECHA disseminated data, 2015).
Based on the available experimental data the hydrolysis product is acutely harmful to algae
Hydrolysis product HCl:
HCl was tested in a semi-static acute toxicity test according to OECD 203 with Cyprinus carpio. The 72-h ErC50 was 0.492 mg/L (acid equivalent to pH 5.3; MITI, 1999; peer reviewed data: OECD SIDS, 2002).
Based on the available experimental data the hydrolysis product HCl is considered to be acutely very toxic for aquatic algae (pH dependent). These data have not been taken into consideration to evaluate aquatic toxicity as observed effects are caused by a pH-shift in the test medium.
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