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Diss Factsheets
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EC number: 229-912-9 | CAS number: 6834-92-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, but no information on purity of test substance
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Version / remarks:
- conforms with OECD 202, part 1
- GLP compliance:
- yes
- Remarks:
- Henkel KGaA, Forschung Biologie/ Produktsicherheit Oekologie.
- Analytical monitoring:
- not specified
- Vehicle:
- yes
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Source: BioInternational B.V. NJ Hoorn,The Netherlands
- Age at study initiation (mean and range, SD): not reported (neonates)
- Method of breeding: incubation of ephipids at 4800 Lux and 19-22°C. The ephipids are grown on M4-Medium according to Elendt. Neonates are incubated at 900 Lux (16h light-8h dark cycle), 20°C and grown on M4-Medium according to Elendt
ACCLIMATION
- Acclimation conditions (same as test or not): yes
- Type and amount of food: green algae Spirula
- Feeding frequency: feeding terminated 3 hrs before start of the test - Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Test temperature:
- 20.3-20.5°C
- pH:
- 7.8-8.0 (adjusted) and 9-11 (not adjusted)
- Nominal and measured concentrations:
- nominal: 100, 300, 1000, 3000, 10000 mg a.s./L
- Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 100 mg/L
- Remarks on result:
- other: pH 7.8-8
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1 700 mg/L
- Remarks on result:
- other: pH 7.8-8
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 10 000 mg/L
- Remarks on result:
- other: pH 7.8-8
- Results with reference substance (positive control):
- Concentrations: not reported - Results: EC50 (24 hr) 0.9-1.9 mg/L for potassium dichromate.
Reference
Effect data (Immobilisation): EC0: 1000 mg/L, EC50: 1700 mg/L and EC100: 3000 mg/L (pH 9-11) EC0: 100 mg/L, EC50: 1700 mg/L and EC100: 10000 mg/L (pH 7.8-8) - Concentration / response curve: not reported - Cumulative immobilisation: not reported - Effect concentration vs. test substance solubility: not reported - Other effects: Not reported RESULTS CONTROL: not reported.
Description of key information
EC50 (48 h): 1700 mg/L (Daphnia magna)
However, for the purpose of risk assessment and as explained in the section on the calculation of Predicted No Effect Concentrations, the PNEC is derived from the ubiquitous SiO2 background concentration in freshwater in Europe, which is 7.5 mg/L.
Key value for chemical safety assessment
Additional information
No study available on sodium metasilicate. Data are read-across to sodium silicate. In a GLP study by Kirch (1997) following EU Guideline 92/69/EWG, which corresponds to OECD guideline 202, part 1, exposure of the freshwater cladoceran Daphnia magna to sodium silicate solutions (MR 3.2, 35 wt %) at pH 9 - 11 and a pH adjusted to 7.8 - 8.0 resulted in a 48 h EC50 of 1700 mg active matter/L in both cases.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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