Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-903-6 | CAS number: 255830-15-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Between 20 May 2012 and 04 October 2012.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions, however no formal claim of GLP compliance was made.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- differential scanning calorimetry
- Key result
- Decomposition:
- yes
- Remarks:
- The test item has been determined to undergo rapid decomposition from approximately 150°C.
- Decomp. temp.:
- ca. 150 °C
- Sublimation:
- no
- Conclusions:
- The test item has been determined to undergo rapid decomposition from approximately 150°C.
- Executive summary:
The determination was carried out by differential scanning calorimetry (DSC) using a procedure designed to be compatible with Method A1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Discussion
Similar thermographic profiles were obtained using air and nitrogen atmospheres; this indicates that the observed decomposition in both determinations is probably thermal and not oxidative.
Conclusion
The test item has been determined undergo rapid decomposition from approximately 150°C.
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- The study was conducted in accordance with a relevant method, but not in compliance with GLP
- GLP compliance:
- not specified
- Type of method:
- thermal analysis
- Decomposition:
- yes
- Decomp. temp.:
- >= 100 - 300 °C
- Conclusions:
- A total weight loss of 12% was observed during thermal analysis of the sample from 100 - 300°C. The result is considered to be reliable.
Referenceopen allclose all
Results
Please see Attachment 1 for Thermograms and Thermographic Data.
During the experiment, there were two significant phenomena; starting from 100 - 200°C, weight loss corresponding to 7.5% was obtained. Also, from 200 - 300°C, weight loss of 4.5% was observed, given a total weight loss of 12% for the sample during the thermal analysis.
Description of key information
Melting point: The acid form (ATMP-N-Oxide acid) was observed to undergo thermal decomposition from approximately 150°C (Atwal 2012, Andreotti 2012). This conclusion is read across to the salt to indicate that ATMP-N-Oxide-5K will also undergo decomposition when heated.
Key value for chemical safety assessment
Additional information
The melting point of the anhydrous form of the parent acid (ATMP-N-Oxide) was determined using differential scanning calorimetry (DSC) in accordance with EU Method A.1 test method. ATMP-N-Oxide acid (anhydrous form) was observed to undergo thermal decomposition from approximately 150°C. The result is considered to be reliable and is selected as key study.
The key study was supported by a second study where the weight loss of ATMP-N-Oxide acid was measured during heating. A thermal decomposition of the parent acid was observed from 100 -300°C, this amounted to a total weight loss of 12% obtained using a TGA-FTIR method.
This results are read-across to the salt, ATMP-N-Oxide-5K, to indicate that the salt will also undergoes thermal decomposition when heated. Salts would be expected to melt at a higher temperature than the parent acid, and to decompose on heating.
A melting/freezing point value of -15°C was reported for an aqueous solution of ATMP-N-Oxide-5K in a secondary source to which no reliability could be assigned.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.