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Diss Factsheets
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EC number: 610-130-5 | CAS number: 436083-99-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Remarks:
- study conducted in Korea by GLP lab but limited information available in English at this time.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide
- EC Number:
- 610-130-5
- Cas Number:
- 436083-99-7
- Molecular formula:
- Amorphous glass consisting of SinO(3n-1)2(n-1) Polymeric anions ionically bonded to Ca2+ and Mg2+ cations or other alkaline earth cations
- IUPAC Name:
- amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide
- Details on test material:
- - Name of test material (as cited in study report): Isofrax, Carbawool(sic)
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Remarks:
- Silica content assessed in test samples using ICP-MS
- Details on sampling:
- Limited information is available.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- loading rate of 100mg/l established in water
Test organisms
- Test organisms (species):
- Oryzias latipes
- Details on test organisms:
- TEST ORGANISM
- Common name: Rice Fish
- Strain: Not applicable
- Source:
- Age at study initiation (mean and range, SD): Not specified
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Remarks on exposure duration:
- Standard as per OECD Guidelines
- Post exposure observation period:
- None required
Test conditions
- Hardness:
- Unknown
- Test temperature:
- Not specified
- Salinity:
- Not specified
- Nominal and measured concentrations:
- Nominal: Control and 100 mg/L nominal loading rate
Measured: The dissolved test item may have been one or several components of the test item. Given that toxicity cannot be attributed to a single component or mixture of components but to the test item as a whole, the results were based on nominal loading rates only. - Details on test conditions:
- no specific details known at this time conducted in accordance with OECD 203
- Reference substance (positive control):
- no
- Remarks:
- Not a guideline requirement
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (total fraction)
- Basis for effect:
- mortality (fish)
- Details on results:
- Mortality: There were no mortalities in fish exposed to a 100 mg/L loading rate for a period of 96 hours.
Sub-lethal effects: There were no sub-lethal effects of exposure observed in fish exposed to a 100 mg/L loading rate for a period of 96 hours. - Results with reference substance (positive control):
- Not applicable
- Reported statistics and error estimates:
- An estimate of the LL50 values was given by inspection of the mortality data.
Any other information on results incl. tables
- Sublethal observations / clinical signs:
no sub lethal observervations reported.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- The test was considered to be valid given that none of the control fish died or showed signs of stress during the test.
- Conclusions:
- The acute toxicity of the test item to the freshwater fish rice fish (Oryzias latipes) has been investigated and gave a 96-Hour LL50 value of greater than 100 mg/L loading rate.
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