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Diss Factsheets
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EC number: 500-062-3 | CAS number: 28390-91-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of the test substance to the aquatic freshwater invertebrate Daphnia magna was studied under GLP in accordance with OECT TG 202.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 4.7 mg/L
Additional information
The test was conducted under semi-static conditions over a period of 48 hours and test medium was exchanged after 24 hours. Tests were conducted with 100 mL glass beakers covered with glass plates. A volume of 50 mL test medium was added to each beaker and four replicates with five daphnids were tested for each concentration. Water accommodated fractions (WAFs) with the loading rates of 6.25, 12.5, 25, 50 and 100 mg/L were tested, which were prepared by adding defined amounts of substance to reconstituted test water (according to ISO 6341) and stirring for 96 hours at room temperature with subsequent filtration of the dispersions through membrane filters with 0.45 µm pore size. Additionally, a control with test medium without test substance was investigated. The concentrations were measured at the begin and the end of each 24-hour period by using HPLC and geometric means of measured concentrations were calculated for each test period. The mean measured (arithmetric means of each geometric means determined for each test period) test concentrations were 3.3, 5.1 and 8.4 mg/L (the concentrations were not measured for the two highest loading rates). The biological results were based on the loading rates and the mean measured concentrations. The 48-hour EL50 was 11 mg/L based on loading rates and the 48-hour EC50 was 4.7 mg/L based on mean measured concentrations.
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