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Diss Factsheets
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EC number: 619-057-3 | CAS number: 94667-33-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- Statement of consulting Laboratory Huntingdon Life Sciences Ltd.: TGD version 4.3.2 final draft, Chapter 2, 3.5 states that temperature dependence is only required “if relevant”. It is our opinion that DMPAP is a highly water-soluble substance and will still be highly water-soluble at 10ºC and 30ºC. Therefore further investigation of this parameter is considered to be unnecessary. Deviations from test method A6 are often required for substances of high solubility.
For example, the use of five-fold excess of test substance produces an over-saturated solution. In cases of substances of high solubility this simply results in a thick suspension or sludge which is often intractable or difficult to separate. Also, the time taken and method employed to separate the phases can affect the solubility result.
Pre-equilibration at 30ºC is not recommended for substances of high solubility it simply induces instant crystallisation and solidification of the test substance to produce an intractable mass on cooling to the test temperature of 20ºC.
Analysis of test substance over different time periods is not required as a limit value of solubility was determined. - GLP compliance:
- yes
- Type of method:
- flask method
- Remarks:
- Modified
- Key result
- Water solubility:
- > 100 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- >= 5 - <= 9
- Remarks on result:
- completely miscible
- Details on results:
- The substance was found to be completely miscible with water at all proportions at room temperaturein the pH range 5 - 9.
- Conclusions:
- The substance was found to be completely miscible with water at all proportions at room temperature. The test substance is completely soluble in water in the pH range 5 - 9.
- Executive summary:
The study was performed in year 2002 in accordance with the Directive 92/69/EEC, Method A6 (flask method) and OECD Guideline No. 105. The substance was found to be completely miscible with water at all proportions at room temperature. The test substance is completely soluble in water in the pH range 5 - 9.
Reference
Description of key information
The test substance is completely soluble in water in the pH range 5 - 9 at room temperature.
Key value for chemical safety assessment
- Water solubility:
- 100 g/L
- at the temperature of:
- 20 °C
Additional information
The substance was found to be completely miscible with water at all proportions at room temperature. The test substance is completely soluble in water in the pH range 5 - 9. Whilst no water solubility value is available for this substance, the maximum value of 100 g/L has been selected as the key value for the chemical safety assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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