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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1957
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Handbook data

Data source

Reference
Reference Type:
review article or handbook
Title:
Acrylamide: It's Preparation and Properties.
Author:
Carpenter, EL and Davies, HS
Year:
1957
Bibliographic source:
J.Appl.Chem., 7, 671 - 676

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Acrylamide
EC Number:
201-173-7
EC Name:
Acrylamide
Cas Number:
79-06-1
Molecular formula:
C3H5NO
IUPAC Name:
prop-2-enamide

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
acetone
Solubility:
631 g/L
Temp.:
30 °C
Medium:
benzene
Solubility:
3.46 g/L
Temp.:
30 °C
Medium:
other: chloroform
Solubility:
26.6 g/L
Temp.:
30 °C
Medium:
other: carbon tetrachloride
Solubility:
0.38 g/L
Temp.:
30 °C
Medium:
other: 1,2-dichloroethane
Solubility:
15 g/L
Temp.:
30 °C
Medium:
ethanol
Solubility:
862 g/L
Temp.:
30 °C
Medium:
ethyl acetate
Solubility:
126 g/L
Temp.:
30 °C
Medium:
other: heptane
Solubility:
0.068 g/L
Temp.:
30 °C
Medium:
methanol
Solubility:
1 555 g/L
Temp.:
30 °C

Applicant's summary and conclusion

Conclusions:
The solubility of acrylamide in organic solvents increases with the polarity of the solvent.