Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-424-9 | CAS number: 120-78-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- The lowest and highest nominal concentrations (3.2 mg/l and 1000 mg/l) were analytically tested direct after the preparation of the solution and after the 48 h exposure time.
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Phylum: Clone culture of the Geman health authority, Berlin.
Laboratory culture of the Bayer AG Leverkusen. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 15.6°dH
- Test temperature:
- 21.0-22°C
- pH:
- 8.0 - 8.2
- Dissolved oxygen:
- 8.3 - 8.9 mg/l
- Nominal and measured concentrations:
- The actual concentrations of test solutions with the lowest (3.2 mg/L) and highest (1000 mg/L) nominal concentrations were analyzed at both the beginning and the end of the exposure. The analyzed results were always below 0.3mg/L.
- Duration:
- 48 h
- Dose descriptor:
- other: EC05
- Effect conc.:
- 54 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 24 - 85 mg/l
- Duration:
- 48 h
- Dose descriptor:
- EC10
- Effect conc.:
- 73 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 37 - 108 mg/l
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 211 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 151 - 294 mg/l
- Conclusions:
- No acute toxicity of MBTS to Daphnia magna was observed up to its water solubility (<=0.3 mg/L) at pH 8.0-8.2 and 21-22°C.
- Executive summary:
No acute toxicity of MBTS to Daphnia magna was observed up to its water solubility (<=0.3 mg/L) at pH 8.0-8.2 and 21-22°C according to EU Method C.2 (Acute Toxicity for Daphnia) (Bayer AG, 1993).
Reference
The actual concentrations of test solutions with the lowest (3.2 mg/L) and highest (1000 mg/L) nominal concentrations were analyzed at both the beginning and the end of the exposure. The analyzed results were always below 0.3mg/L. MBTS has an estimated water solubility in the range of 0.27 - 0.37 mg/L at 25°C and hence the result from this study can be interprated as no effect up to water solubility of MBTS. The observed effect is most probably due to the direct impact from undissolved substance.
Description of key information
No acute toxicity of MBTS to Daphnia magna was observed up to its water solubility (<=0.3 mg/L) at pH 8.0-8.2 and 21-22°C according to EU Method C.2 (Acute Toxicity for Daphnia) (Bayer AG, 1993).
Key value for chemical safety assessment
Additional information
Monsanto (1979) reported a 48h-EC50 of 82 mg/l of MBTS to Daphnia magna without analytical monitoring. This value was based on nominal concentration and precipitations were observed in all concentrations tested from 10 to 100 mg/L; and hence the observed effect is due to both dissolved and undissolved substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)