Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-480-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Carcinogenicity
Administrative data
Description of key information
complex metal containing substance
classification made based on CLP rules for mixtures
solubility of metal constituents is poor
in vitro bio-accessability tests, mimicking gastric fluids
Key value for chemical safety assessment
Justification for classification or non-classification
Copper final slag contains constituents classified as category 1 carcinogens. At typical metal equivalent levels of 0.05% these constituents do not trigger classification for carcinogenicity.
At maximum actual levels up to 0.35%, Co constituents trigger classification of the substance as cat. 1B above the generic classification limit of 0.1%.To further refine the classification in vitro measurements of bio-accessibility in solvent that resembles gastric fluid performed according to ASTM D5517.07 have been completed. The fraction of metals that solubilize under these conditions can be considered as worst case determinant of bio-accessibility of metals contained in the slag. Results demonstrate the reduced relative bio-accessibility of metals in gastric fluids. Absolutebioaccessible concentrations of Co in two final copper slag samples concerned are 0.003% to 0.004 % thus below the concentration limit of 0.1% for carcinogenicity (Carc. 1B).
This assessment was conducted assuming exposure via the oral route. The inhalation route can be considered in general as not relevant for the classification of copper final slags. Copper slag in massive and granular form cannot be inhaled. In the case of fines, and where powder, dust or fumes formed during production and professional uses of copper final slags, the respirable particle content is typically below 22%. Risk management measures are adopted to keep airborne levels of metals below exposure limits. Respiratory protection is required in case respirable dust or fumes are formed.
A separate assessment report on the Human health classification of copper final slag is attached in IUCLID section 13.
Additional information
The copper slag is a complex metal containing substance. It mainly contains iron silicate and silicates of aluminum and calcium . Traces of metals exist in metal, mineral form or included in silicate phases.
Classification derived based on rules for mixtures:
Carcinogenicity: Not classified
Results from calculated classification are further supported (WoE) by consideration of physical chemical properties of the UVCB substance.
Chemistry and mineralogy of the slag (see IUCLID section 4.23 chemical and mineralogical characterization) were taken into account.
Water solubility (IUCLID section 4.8) and Sequential dissolutions (IUCLID 4.23 Chemical assays) furthermore confirmed species present and their solubility behavior.
Copper slag contains As and Co constituents classified as cat. 1A (As) and cat. 1B (Co) carcinogens. At typical metal equivalent levels of 0.05% these constituents do not trigger classification for carcinogenicity.
In vitro measurements of bio-accessibility in solvent that resembles gastric fluid performed according to ASTM D5517.07. The fraction of metals that solubilize under these conditions can be considered as worst case determinant of bio-associability of metals contained in the slag. Results demonstrate the reduced relative bio-accessibility of metals thus further confirm the classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.