Registration Dossier
Registration Dossier
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EC number: 202-532-0 | CAS number: 96-76-4
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Based upon the results of a flow through fresh water test (MITI 1992) conducted over 8 weeks with Cyprinus carpio at two nominal concentration levels, 2 µg/l (135-360 L/kg) and 20 µg/l (128-436 L/kg), it can be concluded that 2,4-di-tert-butylphenol has a moderate bioaccumulation potential.
Using the BCFWIN (v3.0) model with a measured Log Kow value of 4.8, the BCF fish is predicted to be 409 L/kg wwt for 2,4-DTBP. This predicted BCF fish is consistent with the experimental values obtained in the MITI study and therefore the worst case experimental value of 436 L/kg in fish will be used in the risk assessment.
The TGD calculations have been shown to be very conservative, estimating a BCF for fish of 2400 L/kg wwt. However, as there are no experimental data available for BCF in earthworms, the TGD calculated BCF earthworm of 758 L/kg wwt, will be used in the risk assessment.
Key value for chemical safety assessment
- BCF (aquatic species):
- 436 L/kg ww
Additional information
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