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EC number: 402-860-6 | CAS number: 110553-27-0 CG 25-1320; IRGANOX 1520; TK 12229/1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
No toxic effects in the range of water solubility
The aquatic toxicity of 4,6-bis(octylthiomethyl)-o-cresol has been extensively tested towards various organisms. The following table reflects the outcome of these tests:
Test organism |
Test duration |
Effect parameter |
Effect value (mg/L) |
Nominal/ |
OECD guideline |
Vehicle |
Remarks |
Brachydanio rerio |
96h |
LC50 |
>100 |
nominal |
203 |
yes |
No effects at the highest test concentrations |
Daphnia magna |
24h |
LC50 |
Not reliable |
nominal |
202 |
yes |
Calculation of EC50 was not possible |
Daphnia magna |
21d |
NOEC |
>=0.0088 |
measured |
211 |
no |
No effects up to the highest test concentration |
Scenedesmus subspicatus |
72h |
LC50 |
>100 |
nominal |
201 |
no |
No effects at the highest test concentrations |
It should be noted, that due to the low water solubility and high adsorptivity, 4,6-bis(octylthiomethyl)-o-cresol is difficult to test. In some cases water accomodated fractions of supersaturated emulsions were tested without the use of vehicles. On the other hand, some tests were performed using solvents. Therefore, the interpretation of these aquatic toxicity tests should be taken with care.
Nevertheless, no toxic effects of 4,6-bis(octylthiomethyl)-o-cresol were observed at the highest test substance concentrations among all tests. Therefore, the test substance is not toxic within or even well above its limit of water solubility.
The toxicity towards aquatic bacteria, was also tested. In a short term respiration test according to OECD guideline 209, no effects on activated sludge were detected at the highest test concentration (100 mg/L). Therefore, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
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